MGTX insider transactions

CFO & COO Giroux Richard gifted 7,000 units of Ordinary Shares, decreasing direct ownership by 0.72% to 964,530 units (SEC Form 4)

PRESIDENT & CEO Forbes Alexandria sold $568,540 worth of Ordinary Shares (62,000 units at $9.17) as part of a pre-agreed trading plan, decreasing direct ownership by 4% to 1,387,695 units (SEC Form 4)

SEC Form 4 filed by CHIEF DEVELOPMENT OFFICER Fleck Penny Renee

SEC Form 3 filed by new insider Fleck Penny Renee

Amendment: CHIEF MEDICAL OFFICER Zeldin Robert K covered exercise/tax liability with 7,814 units of Ordinary Shares, decreasing direct ownership by 5% to 146,204 units (SEC Form 4)

Director Perceptive Advisors Llc was granted 555,555 units of Ordinary Shares (SEC Form 4)

SEC Form 4 filed by Giroux Richard

SEC Form 4 filed by Naylor Stuart

SEC Form 4 filed by Forbes Alexandria

CHIEF MEDICAL OFFICER Zeldin Robert K converted options into 7,500 units of Ordinary Shares and covered exercise/tax liability with 2,952 units of Ordinary Shares, increasing direct ownership by 3% to 172,888 units (SEC Form 4)

GENERAL COUNSEL AND SECRETARY Wollin Robert J converted options into 11,250 units of Ordinary Shares and covered exercise/tax liability with 5,949 units of Ordinary Shares, increasing direct ownership by 10% to 57,377 units (SEC Form 4)

CHIEF DEV. OFFICER Naylor Stuart converted options into 25,000 units of Ordinary Shares and covered exercise/tax liability with 11,750 units of Ordinary Shares, increasing direct ownership by 2% to 696,166 units (SEC Form 4)

CFO & COO Giroux Richard converted options into 60,000 units of Ordinary Shares and covered exercise/tax liability with 31,726 units of Ordinary Shares, increasing direct ownership by 3% to 1,027,530 units (SEC Form 4)

PRESIDENT & CEO Forbes Alexandria covered exercise/tax liability with 33,048 units of Ordinary Shares and converted options into 62,500 units of Ordinary Shares, increasing direct ownership by 2% to 1,511,695 units (SEC Form 4)

CHIEF MEDICAL OFFICER Zeldin Robert K converted options into 35,000 units of Ordinary Shares and covered exercise/tax liability with 13,951 units of Ordinary Shares, increasing direct ownership by 14% to 168,340 units (SEC Form 4)

GENERAL COUNSEL AND SECRETARY Wollin Robert J converted options into 50,000 units of Ordinary Shares and covered exercise/tax liability with 27,206 units of Ordinary Shares, increasing direct ownership by 78% to 52,076 units (SEC Form 4)

CHIEF DEV. OFFICER Naylor Stuart covered exercise/tax liability with 35,250 units of Ordinary Shares and converted options into 75,000 units of Ordinary Shares, increasing direct ownership by 6% to 682,916 units (SEC Form 4)

CFO & COO Giroux Richard converted options into 310,000 units of Ordinary Shares and covered exercise/tax liability with 163,916 units of Ordinary Shares, increasing direct ownership by 17% to 999,256 units (SEC Form 4)

PRESIDENT & CEO Forbes Alexandria converted options into 310,000 units of Ordinary Shares and covered exercise/tax liability with 163,916 units of Ordinary Shares, increasing direct ownership by 11% to 1,482,243 units (SEC Form 4)

CHIEF MEDICAL OFFICER Zeldin Robert K converted options into 17,500 units of Ordinary Shares and covered exercise/tax liability with 6,729 units of Ordinary Shares, increasing direct ownership by 8% to 147,291 units (SEC Form 4)

GENERAL COUNSEL AND SECRETARY Wollin Robert J converted options into 7,500 units of Ordinary Shares and covered exercise/tax liability with 4,364 units of Ordinary Shares, increasing direct ownership by 12% to 29,282 units (SEC Form 4)

CHIEF DEV. OFFICER Naylor Stuart converted options into 37,500 units of Ordinary Shares and covered exercise/tax liability with 17,625 units of Ordinary Shares, increasing direct ownership by 3% to 643,166 units (SEC Form 4)

CFO & COO Giroux Richard converted options into 52,500 units of Ordinary Shares and covered exercise/tax liability with 28,822 units of Ordinary Shares, increasing direct ownership by 3% to 853,172 units (SEC Form 4)

PRESIDENT & CEO Forbes Alexandria converted options into 62,500 units of Ordinary Shares and covered exercise/tax liability with 34,074 units of Ordinary Shares, increasing direct ownership by 2% to 1,336,159 units (SEC Form 4)

Director Perceptive Advisors Llc returned $18,193,000 worth of Ordinary Shares to the company (2,300,000 units at $7.91) (SEC Form 4)

PRESIDENT & CEO Forbes Alexandria gifted 6,250 units of Ordinary Shares, decreasing direct ownership by 0.48% to 1,307,733 units (SEC Form 4)

GENERAL COUNSEL AND SECRETARY Wollin Robert J gifted 5,000 units of Ordinary Shares, decreasing direct ownership by 16% to 26,146 units (SEC Form 4)

CFO & COO Giroux Richard sold $212,880 worth of Ordinary Shares (24,000 units at $8.87), decreasing direct ownership by 3% to 829,494 units (SEC Form 4)

PRESIDENT & CEO Forbes Alexandria sold $398,525 worth of Ordinary Shares (47,500 units at $8.39), decreasing direct ownership by 3% to 1,313,983 units (SEC Form 4)

CFO & COO Giroux Richard sold $204,480 worth of Ordinary Shares (24,000 units at $8.52), decreasing direct ownership by 3% to 853,494 units (SEC Form 4)

PRESIDENT & CEO Forbes Alexandria sold $378,575 worth of Ordinary Shares (47,500 units at $7.97), decreasing direct ownership by 3% to 1,361,483 units (SEC Form 4)

CFO & COO Giroux Richard gifted 5,000 units of Ordinary Shares, decreasing direct ownership by 0.57% to 877,494 units (SEC Form 4)

SEC Form 4 filed by Director Yu Debra

SEC Form 4 filed by Director Shenk Thomas E

SEC Form 4 filed by Director Seligman Nicole

SEC Form 4 filed by Director Mendoza Neil

SEC Form 4 filed by Director Hukkelhoven Ellen

Amendment: SEC Form 4 filed by Director Harris Keith R.

SEC Form 4 filed by Director Harris Keith R.

SEC Form 4 filed by Director Perceptive Advisors Llc

Director Harris Keith R. converted options into 75,000 units of Ordinary Shares, increasing direct ownership by 150% to 125,000 units (SEC Form 4)

CFO & COO Giroux Richard sold $144,000 worth of Ordinary Shares (24,000 units at $6.00), decreasing direct ownership by 3% to 882,494 units (SEC Form 4)

PRESIDENT & CEO Forbes Alexandria sold $253,650 worth of Ordinary Shares (47,500 units at $5.34), decreasing direct ownership by 3% to 1,408,983 units (SEC Form 4)

SEC Form 4 filed by CFO & COO Giroux Richard

SEC Form 4 filed by CHIEF MEDICAL OFFICER Zeldin Robert K

SEC Form 4 filed by PRESIDENT & CEO Forbes Alexandria

SEC Form 4 filed by GENERAL COUNSEL AND SECRETARY Wollin Robert J

SEC Form 4 filed by CHIEF DEV. OFFICER Naylor Stuart

CHIEF MEDICAL OFFICER Zeldin Robert K converted options into 15,000 units of Ordinary Shares and covered exercise/tax liability with 5,903 units of Ordinary Shares, increasing direct ownership by 7% to 136,520 units (SEC Form 4)

GENERAL COUNSEL AND SECRETARY Wollin Robert J converted options into 22,500 units of Ordinary Shares and covered exercise/tax liability with 12,116 units of Ordinary Shares, increasing direct ownership by 50% to 31,146 units (SEC Form 4)

CHIEF DEV. OFFICER Naylor Stuart converted options into 50,000 units of Ordinary Shares and covered exercise/tax liability with 23,500 units of Ordinary Shares, increasing direct ownership by 4% to 623,291 units (SEC Form 4)

CFO & COO Giroux Richard converted options into 120,000 units of Ordinary Shares and covered exercise/tax liability with 63,452 units of Ordinary Shares, increasing direct ownership by 7% to 906,495 units (SEC Form 4)

PRESIDENT & CEO Forbes Alexandria converted options into 125,000 units of Ordinary Shares and covered exercise/tax liability with 66,095 units of Ordinary Shares, increasing direct ownership by 4% to 1,456,483 units (SEC Form 4)

CFO & COO Giroux Richard sold $150,960 worth of Ordinary Shares (24,000 units at $6.29), decreasing direct ownership by 3% to 849,947 units (SEC Form 4)

CHIEF MEDICAL OFFICER Zeldin Robert K converted options into 37,500 units of Ordinary Shares and covered exercise/tax liability with 15,149 units of Ordinary Shares, increasing direct ownership by 21% to 127,423 units (SEC Form 4)

GENERAL COUNSEL AND SECRETARY Wollin Robert J converted options into 5,000 units of Ordinary Shares and covered exercise/tax liability with 2,909 units of Ordinary Shares, increasing direct ownership by 11% to 20,762 units (SEC Form 4)

CHIEF DEV. OFFICER Naylor Stuart converted options into 23,750 units of Ordinary Shares and covered exercise/tax liability with 11,163 units of Ordinary Shares, increasing direct ownership by 2% to 596,791 units (SEC Form 4)

CFO & COO Giroux Richard covered exercise/tax liability with 13,219 units of Ordinary Shares and converted options into 25,000 units of Ordinary Shares, increasing direct ownership by 1% to 873,947 units (SEC Form 4)

PRESIDENT & CEO Forbes Alexandria covered exercise/tax liability with 15,863 units of Ordinary Shares and converted options into 30,000 units of Ordinary Shares, increasing direct ownership by 1% to 1,397,578 units (SEC Form 4)

CHIEF MEDICAL OFFICER Zeldin Robert K converted options into 17,500 units of Ordinary Shares and covered exercise/tax liability with 6,886 units of Ordinary Shares, increasing direct ownership by 11% to 105,072 units (SEC Form 4)