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2025-09-152025-12-16
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25 items- PRVaccinex, Inc. Announces $60 million Agreement to Finance a Phase 2b clinical trial of pepinemab to treat Alzheimer's DiseaseROCHESTER, N.Y., Dec. 23, 2025 (GLOBE NEWSWIRE) -- Vaccinex, Inc. (VCNX), a clinical-stage biotechnology company pioneering a differentiated approach to treating Alzheimer's disease (AD) by inhibiting semaphorin 4D (SEMA4D) induced pathology in brain, today announced that it has entered into a $60 million revenue sharing agreement with Pepinemab Development Venture, LP (PDV) to continue advancing development of its pepinemab anti-SEMA4D antibody in an enlarged phase 2b clinical trial for treatment of AD. PDV LP is an investment entity established by FCMI, an existing Vaccinex investor. Albert Friedberg is Chairman of FCMI and of the Vaccinex Board. The agreements provide that, in exchange
- PRVaccinex to Report Promising New Clinical Results of Neoadjuvant Treatment with Pepinemab to Enhance Immunotherapy in Patients with Head and Neck Cancer at ASCO Annual MeetingROCHESTER, N.Y., May 27, 2025 (GLOBE NEWSWIRE) -- Vaccinex, Inc. (NASDAQ:VCNX), a clinical-stage biotechnology company pioneering a differentiated approach to treating cancer and Alzheimer's disease (AD) through the inhibition of Semaphorin 4D (SEMA4D), today announced that it will present new data characterizing the unique mechanism of pepinemab to enhance immune responses to checkpoint therapies in the neoadjuvant setting that are associated with improved pathologic response in patients with head and neck cancer. Lead investigator and collaborator, Conor Steuer, MD from Winship Cancer Center at Emory University, will present results at the 2025 Annual Meeting of Clinical Oncology (ASCO)
- PRVaccinex to Report Promising New Clinical Data Revealing Pepinemab's Unique Mechanism to Enhance Immunotherapy at Annual Meeting of American Association for Cancer Research (AACR)Neoadjuvant treatment with pepinemab appears to induce abundant, mature lymphoid structures that correlate with durable clinical benefit of immunotherapy in patients with metastatic melanoma. Pepinemab, Semaphorin 4D blocking immunotherapy, also appears to induce the formation of efficient lymphoid structures in "cold" tumors of patients with recurrent and metastatic head and neck cancer. ROCHESTER, N.Y., April 21, 2025 (GLOBE NEWSWIRE) -- Vaccinex, Inc. (NASDAQ:VCNX), a clinical-stage biotechnology company pioneering a differentiated approach to treating cancer and Alzheimer's disease (AD) through the inhibition of Semaphorin 4D (SEMA4D), today announced that it will present exciting ne
- SECSEC Form 10-K filed by Vaccinex Inc.10-K - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form NT 10-K filed by Vaccinex Inc.NT 10-K - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form 15-12G filed by Vaccinex Inc.15-12G - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form EFFECT filed by Vaccinex Inc.EFFECT - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form EFFECT filed by Vaccinex Inc.EFFECT - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form EFFECT filed by Vaccinex Inc.EFFECT - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form EFFECT filed by Vaccinex Inc.EFFECT - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form EFFECT filed by Vaccinex Inc.EFFECT - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form EFFECT filed by Vaccinex Inc.EFFECT - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form EFFECT filed by Vaccinex Inc.EFFECT - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form EFFECT filed by Vaccinex Inc.EFFECT - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form EFFECT filed by Vaccinex Inc.EFFECT - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form EFFECT filed by Vaccinex Inc.EFFECT - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form EFFECT filed by Vaccinex Inc.EFFECT - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form EFFECT filed by Vaccinex Inc.EFFECT - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form EFFECT filed by Vaccinex Inc.EFFECT - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form EFFECT filed by Vaccinex Inc.EFFECT - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form EFFECT filed by Vaccinex Inc.EFFECT - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form POS AM filed by Vaccinex Inc.POS AM - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form POS AM filed by Vaccinex Inc.POS AM - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form POS AM filed by Vaccinex Inc.POS AM - VACCINEX, INC. (0001205922) (Filer)
- SECSEC Form POS AM filed by Vaccinex Inc.POS AM - VACCINEX, INC. (0001205922) (Filer)