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PR09:00:00·12h·Health Care·
$AGIO
Agios Showcases RISE UP Phase 3 Results at EHA 2026 Plenary Session Reinforcing Strong Anti-Hemolytic Profile of Mitapivat in Sickle Cell Disease
Mitapivat demonstrated statistically significant improvement in hemoglobin response compared with placebo, with rapid onset and durable effectsNew analyses showed patients in mitapivat arm had clinically meaningful reduction in transfusion burden compared with placeboPatients in mitapivat arm who achieved hemoglobin response had clinically meaningful benefits across measures of sickle cell pain crises, fatigue, and other patient-reported outcomesMitapivat was well-tolerated, with a safety profile consistent with previous trials of mitapivat in sickle cell diseaseCompany to host investor conference call and webcast today at 9:00 a.m. ET (3:00 p.m. CEST) CAMBRIDGE, Mass., June 13, 2026 (GLO
PR08:01:00·13h·Health Care·
$RYTM
Rhythm Pharmaceuticals Presents Positive Interim Six-month Data from Phase 2 Trial of Setmelanotide in Patients with Prader-Willi Syndrome (PWS) at ENDO 2026
-- Patients with PWS treated with setmelanotide therapy (N=17) achieved clinically meaningful BMI or BMI z-score reductions, reductions in fat mass with preservation of lean mass, and improvements in hyperphagia and anxiety measures -- -- Positive results reinforce rationale for Phase 3 development of MC4R agonism in PWS -- -- Company to hold conference call on Saturday, June 13, at 8 a.m. CT, 9 a.m. ET -- BOSTON, June 13, 2026 (GLOBE NEWSWIRE) -- Rhythm Pharmaceuticals, Inc. (NASDAQ:RYTM), a global commercial-stage biopharmaceutical company focused on transforming the lives of patients living with rare neuroendocrine diseases, today announced preliminary data from a Phase 2 trial
INSIDER21:58:25·23h·Technology·
$PCOR
Chairman of the Board Courtemanche Craig F. Jr. exercised 56,122 shares at a strike of $2.42 and sold $2,533,545 worth of shares (56,122 units at $45.14) as part of a pre-agreed trading plan (SEC Form 4)
4 - PROCORE TECHNOLOGIES, INC. (0001611052) (Issuer)
INSIDER21:55:05·23h·Technology·
$IONQ
CFO & COO Singh Inder M covered exercise/tax liability with 6,272 shares, decreasing direct ownership by 1% to 417,503 units (SEC Form 4)
4 - IonQ, Inc. (0001824920) (Issuer)
INSIDER21:55:03·23h·Technology·
$IONQ
Executive Chair, IonQ Federal Cardillo Robert T. covered exercise/tax liability with 904 shares, decreasing direct ownership by 0.65% to 139,063 units (SEC Form 4)
4 - IonQ, Inc. (0001824920) (Issuer)
INSIDER21:55:05·23h·Technology·
$IONQ
President and CEO De Masi Niccolo covered exercise/tax liability with 16,120 shares, decreasing direct ownership by 1% to 1,139,547 units (SEC Form 4)
4 - IonQ, Inc. (0001824920) (Issuer)
INSIDER21:55:07·23h·Industrials·
$GRMN
Executive Chairman Kao Min H gifted 11,005 units of Registered Shares (SEC Form 4)
4 - GARMIN LTD (0001121788) (Issuer)
INSIDER21:55:03·23h·Technology·
$IONQ
CAO, CLO and Secretary Dacier Paul T covered exercise/tax liability with 4,110 shares, decreasing direct ownership by 4% to 104,458 units (SEC Form 4)
4 - IonQ, Inc. (0001824920) (Issuer)
INSIDER21:50:45·23h·Consumer Discretionary·
$GOLF
Principal Accounting Officer Mohamed Nicholas N sold $50,241 worth of shares (529 units at $95.00), decreasing direct ownership by 16% to 2,868 units (SEC Form 4)
4 - Acushnet Holdings Corp. (0001672013) (Issuer)
INSIDER21:44:15·23h·Health Care·
$PRKS
Chief Commercial Officer Finazzo Christopher L. sold $294,080 worth of shares (8,000 units at $36.76), decreasing direct ownership by 6% to 130,285 units (SEC Form 4)
4 - United Parks & Resorts Inc. (0001564902) (Issuer)
INSIDER21:43:47·23h·Health Care·
$PRKS
Officer Miller Kyle Robert was granted 12,459 shares, increasing direct ownership by 32% to 51,954 units (SEC Form 4)
4 - United Parks & Resorts Inc. (0001564902) (Issuer)
INSIDER21:43:06·23h·Health Care·
$PRKS
Officer Forrester James W Jr was granted 1,245 shares, increasing direct ownership by 5% to 27,883 units (SEC Form 4)
4 - United Parks & Resorts Inc. (0001564902) (Issuer)
INSIDER21:30:56·1d·Technology·
$KULR
General Counsel & Secretary Yamamoto Jay Koichi covered exercise/tax liability with 9,507 shares, decreasing direct ownership by 5% to 168,500 units (SEC Form 4) (withholding obligation)
4 - KULR Technology Group, Inc. (0001662684) (Issuer)
INSIDER21:30:10·1d·Technology·
$KULR
New insider Perez Steven John claimed ownership of 1,250 shares (SEC Form 3)
3 - KULR Technology Group, Inc. (0001662684) (Issuer)
INSIDER21:21:06·1d·Telecommunications·
$ROKU
Director Luna Gina converted options into 1,847 shares, increasing direct ownership by 30% to 7,955 units (SEC Form 4)
4 - ROKU, INC (0001428439) (Issuer)
INSIDER21:17:43·1d·Consumer Discretionary·
$TK
President and CEO Hvid Kenneth sold $82,146 worth of shares (6,822 units at $12.04), decreasing direct ownership by 6% to 105,500 units (SEC Form 4)
4 - TEEKAY CORP LTD (0000911971) (Issuer)
INSIDER21:17:13·1d·Telecommunications·
$ROKU
Director Blackburn Jeffrey M converted options into 1,847 shares, increasing direct ownership by 15% to 14,040 units (SEC Form 4)
4 - ROKU, INC (0001428439) (Issuer)
INSIDER21:14:42·1d·Telecommunications·
$ROKU
Director Fyfield Mai converted options into 1,847 shares and sold $99,540 worth of shares (832 units at $119.64), increasing direct ownership by 23% to 5,389 units (SEC Form 4) (withholding tax)
4 - ROKU, INC (0001428439) (Issuer)
INSIDER21:13:32·1d·Telecommunications·
$ROKU
Director Hodrick Laurie Simon converted options into 1,847 shares, increasing direct ownership by 30% to 7,955 units (SEC Form 4)
4 - ROKU, INC (0001428439) (Issuer)
INSIDER21:12:57·1d·Health Care·
$SNSE
SEC Form 4 filed by President & PEO Gerry Christopher
4 - Sensei Biotherapeutics, Inc. (0001829802) (Issuer)