POS EX 1 jpc-posex_042126.htm POST-EFFECTIVE AMENDMENT

As filed with the Securities and Exchange Commission on April 21, 2026

File No. 333-286736

UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

FORM N-14

REGISTRATION STATEMENT
UNDER
THE SECURITIES ACT OF 1933

☐ Pre-Effective Amendment No. __

☒ Post-Effective Amendment No. 1

NUVEEN PREFERRED & INCOME OPPORTUNITIES FUND

(Exact Name of Registrant as Specified in Charter)

333 West Wacker Drive
Chicago, Illinois 60606
(Address of Principal Executive Offices: Number, Street, City, State, Zip Code)

(800) 257-8787
(Area Code and Telephone Number)

Mark L. Winget
Vice President and Secretary
Nuveen Investments
333 West Wacker Drive
Chicago, Illinois 60606
(Name and Address of Agent for Service)

Copies to:

Deborah Bielicke Eades

Vedder Price P.C.

222 North LaSalle Street

Chicago, Illinois 60601

Eric F. Fess

Chapman and Cutler LLP

320 South Canal Street, 27th Floor

Chicago, Illinois 60606

EXPLANATORY NOTE

The Joint Proxy Statement/Prospectus and Statement of Additional Information, each in the form filed on June 11, 2025, pursuant to Rule 424 of the General Rules and Regulations under the Securities Act of 1933, as amended (File No. 333-286736), are incorporated herein by reference.

This amendment is being filed for the sole purpose of adding to Part C of the Registration Statement the executed tax opinion of Vedder Price P.C., supporting the tax matters discussed in the Joint Proxy Statement/Prospectus as Exhibit 12.

PART C
OTHER INFORMATION

Item 15. Indemnification

Section 4 of Article XII of Registrant’s Declaration of Trust, as amended, provides as follows:

Subject to the exceptions and limitations contained in this Section 4, every person who is, or has been, a Trustee, officer, employee or agent of the Trust, including persons who serve at the request of the Trust as directors, trustees, officers, employees or agents of another organization in which the Trust has an interest as a shareholder, creditor or otherwise (hereinafter referred to as a “Covered Person”), shall be indemnified by the Trust to the fullest extent permitted by law against liability and against all expenses reasonably incurred or paid by him in connection with any claim, action, suit or proceeding in which he becomes involved as a party or otherwise by virtue of his being or having been such a Trustee, director, officer, employee or agent and against amounts paid or incurred by him in settlement thereof.

No indemnification shall be provided hereunder to a Covered Person:

(a) against any liability to the Trust or its Shareholders by reason of a final adjudication by the court or other body before which the proceeding was brought that he engaged in willful misfeasance, bad faith, gross negligence or reckless disregard of the duties involved in the conduct of his office;

(b) with respect to any matter as to which he shall have been finally adjudicated not to have acted in good faith in the reasonable belief that his action was in the best interests of the Trust; or

(c) in the event of a settlement or other disposition not involving a final adjudication (as provided in paragraph (a) or (b)) and resulting in a payment by a Covered Person, unless there has been either a determination that such Covered Person did not engage in willful misfeasance, bad faith, gross negligence or reckless disregard of the duties involved in the conduct of his office by the court or other body approving the settlement or other disposition or a reasonable determination, based on a review of readily available facts (as opposed to a full trial-type inquiry), that he did not engage in such conduct:

(i) by a vote of a majority of the Disinterested Trustees acting on the matter (provided that a majority of the Disinterested Trustees then in office act on the matter); or

(ii) by written opinion of independent legal counsel.

The rights of indemnification herein provided may be insured against by policies maintained by the Trust, shall be severable, shall not affect any other rights to which any Covered Person may now or hereafter be entitled, shall continue as to a person who has ceased to be such a Covered Person and shall inure to the benefit of the heirs, executors and administrators of such a person. Nothing contained herein shall affect any rights to indemnification to which Trust personnel other than Covered Persons may be entitled by contract or otherwise under law.

Expenses of preparation and presentation of a defense to any claim, action, suit or proceeding subject to a claim for indemnification under this Section 4 shall be advanced by the Trust prior to final disposition thereof upon receipt of an undertaking by or on behalf of the recipient to repay such amount if it is ultimately determined that he is not entitled to indemnification under this Section 4, provided that either:

(a) such undertaking is secured by a surety bond or some other appropriate security or the Trust shall be insured against losses arising out of any such advances; or

(b) a majority of the Disinterested Trustees acting on the matter (provided that a majority of the Disinterested Trustees then in office act on the matter) or independent legal counsel in a written opinion shall determine, based upon a review of the readily available facts (as opposed to a full trial-type inquiry), that there is reason to believe that the recipient ultimately will be found entitled to indemnification.

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As used in this Section 4, a “Disinterested Trustee” is one (x) who is not an Interested Person of the Trust (including, as such Disinterested Trustee, anyone who has been exempted from being an Interested Person by any rule, regulation or order of the Commission), and (y) against whom none of such actions, suits or other proceedings or another action, suit or other proceeding on the same or similar grounds is then or has been pending.

As used in this Section 4, the words “claim,” “action,” “suit” or “proceeding” shall apply to all claims, actions, suits, proceedings (civil, criminal, administrative or other, including appeals), actual or threatened; and the word “liability” and “expenses” shall include without limitation, attorneys’ fees, costs, judgments, amounts paid in settlement, fines, penalties and other liabilities.

The trustees and officers of the Registrant are covered by joint errors and omissions insurance policies against liability and expenses of claims of wrongful acts arising out of their position with the Registrant and other Nuveen funds, subject to such policies’ coverage limits, exclusions and retention.

Insofar as the indemnification for liabilities arising under the Securities Act of 1933, as amended, (the “1933 Act”) may be permitted to the officers, trustees or controlling persons of the Registrant pursuant to the Declaration of Trust of the Registrant or otherwise, the Registrant has been advised that in the opinion of the Securities and Exchange Commission such indemnification is against public policy as expressed in the 1933 Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by the Registrant of expenses incurred or paid by an officer or trustee or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such officer, trustee or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question of whether such indemnification by it is against public policy as expressed in the 1933 Act and will be governed by the final adjudication of such issue.

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Item 16. Exhibits

(1)(a)

Declaration of Trust dated January 27, 2003. (1)

(1)(b)

Amended and Restated Declaration of Trust of Registrant, dated May 7, 2007. (2)

(1)(c)

Amended and Restated Declaration of Trust of Registrant, dated April 2, 2012. (2)

(2)(a)

Amended and Restated By-Laws of Registrant, dated October 5, 2020. (3)

(2)(b)

Amendment to the Amended and Restated By-Laws of Registrant, dated February 24, 2022. (4)

(2)(c)

Amended and Restated By-Laws of Registrant, dated February 28, 2024. (5)

(3)

Not applicable.

(4)

Form of Agreement and Plan of Merger as Appendix A to the Joint Proxy Statement/Prospectus constituting Part A of the Registration Statement. (17)

(5)

Not applicable.

(6)(a)

Investment Management Agreement, dated October 1, 2014. (2)

(6)(b)

Renewal of Investment Management Agreement, dated July 28, 2015. (2)

(6)(c)

Renewal of Investment Management Agreement, dated July 27, 2016. (2)

(6)(d)

Renewal of Investment Management Agreement, dated July 24, 2017. (6)

(6)(e)

Renewal of Investment Management Agreement, dated July 24, 2018. (7)

(6)(f)

Continuance of Investment Management Agreement, dated July 30, 2019. (8)

(6)(g)

Continuance of Investment Management Agreement, dated July 30, 2020. (9)

(6)(h)

Continuance of Investment Management Agreement, dated July 30, 2021. (10)

(6)(i)

Continuance of Investment Management Agreement, dated July 29, 2022. (11)

(6)(j)

Continuance of Investment Management Agreement, dated July 31, 2023. (12)

(6)(k)

Continuance of Investment Management Agreement, dated May 1, 2024. (16)

(6)(l)

Investment Sub-Advisory Agreement, dated October 1, 2014. (2)

(6)(m)

Notice of Continuance of Investment Sub-Advisory Agreement, dated July 28, 2015 (2)

(6)(n)

Notice of Continuance of Investment Sub-Advisory Agreement, dated July 28, 2016. (2)

(6)(o)

Notice of Continuance of Investment Sub-Advisory Agreement, dated July 24, 2017. (6)

(6)(p)

Notice of Continuance of Investment Sub-Advisory Agreement, dated July 24, 2018. (7)

(6)(q)

Notice of Continuance of Investment Sub-Advisory Agreement, dated July 24, 2019. (8)

(6)(r)

Notice of Continuance of Investment Sub-Advisory Agreement, dated July 31, 2020. (9)

(6)(s)

Notice of Continuance of Investment Sub-Advisory Agreement, dated July 30, 2021. (10)

(6)(t)

Notice of Continuance of Investment Sub-Advisory Agreement, dated July 29, 2022. (11)

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(6)(u)

Notice of Continuance of Investment Sub-Advisory Agreement, dated July 31, 2023. (12)

(6)(v)

Notice of Continuance of Investment Sub-Advisory Agreement, dated April 30, 2024. (16)

(6)(w)

Rule 12d1-4 Investment Agreement between RiverNorth Funds as Acquiring Funds and Nuveen CEFs as Acquiring Funds, dated January 19, 2022. (13)

(7)(a)

Distribution Agreement between the Registrant and Nuveen Securities, LLC, dated March 18, 2021. (14)

(7)(b)

Dealer Agreement between Registrant and Nuveen Securities, LLC and Stifel, Nicolaus & Company Incorporated, dated March 18, 2021. (14)

(8)

Amended and Restated Nuveen Open-End and Closed-End Funds Deferred Compensation Plan for Independent Directors and Trustees, dated May 8, 2020. (3)

(9)(a)

Amended and Restated Master Custodian Agreement between the Nuveen Investment Companies and State Street Bank and Trust Company, dated July 15, 2015. (2)

(9)(b)

Amendment and revised Appendix A to Amended and Restated Master Custodian Agreement, dated July 31, 2020. (3)

(9)(c)

Amendment and revised Appendix A to Amended and Restated Master Custodian Agreement, dated October 7, 2021. (15)

(10)

Not applicable.

(11)

Opinion and Consent of Counsel. (17)

(12)

Opinion and Consent of Vedder Price P.C. supporting the tax matters discussed in the Joint Proxy Statement/Prospectus, is filed herewith.

(13)(a)

Transfer Agency and Service Agreement, dated June 15, 2017 between Registrant and Computershare Inc. and Computershare Trust Company, N.A. (3)

(13)(b)

First Amendment and updated Schedule A, dated September 7, 2017, to the Transfer Agency Service Agreement between the Registrant and Computershare, Inc. and Computershare Trust Company, N.A., dated June 15, 2017. (3)

(13)(c)

Second Amendment and updated Schedule A, dated February 26, 2018 to the Transfer Agency Service Agreement between the Registrant and Computershare, Inc. and Computershare Trust Company, N.A., dated June 15, 2017. (3)

(13)(d)

Third Amendment and updated Schedule A, dated May 11, 2020 to the Transfer Agency Service Agreement between the Registrant and Computershare, Inc. and Computershare Trust Company, N.A., dated June 15, 2017. (3)

(14)

Consent of KPMG LLP, independent registered public accounting firm. (17)

(15)

Not applicable.

(16)

Powers of Attorney. (16)

(17)

Form of Proxy appears following the Joint Proxy Statement/Prospectus constituting Part A of the Registration Statement. (17)

(18)

Calculation of Filing Fee Tables. (17)

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(1)

Filed on January 31, 2003 as an exhibit to the Registrant’s Registration Statement on Form N-2 (File No. 333-102903) and incorporated by reference herein.

(2)

Filed on December 13, 2016 as an exhibit to the Registrant’s Registration Statement on Form N-14 (File No. 333-215072) and incorporated by reference herein.

(3)

Filed on March 19, 2021 as an exhibit to the Registrant’s Registration Statement on Form N-2 (File No. 333-254473) and incorporated by reference herein.

(4)

Filed on February 25, 2022 as an exhibit to the Registrant’s Form 8-K (File no. 811-21293) and incorporated by reference herein.

(5)

Filed on March 6, 2024 as an exhibit to the Registrant’s Form 8-k (File No. 811-21293) and incorporated by reference herein.

(6)

Filed on November 16, 2017 as an exhibit to Post-Effective Amendment No. 1 to Nuveen California AMT-Free Quality Municipal Income Fund’s Registration Statement on Form N-2 (File No. 333-184971) and incorporated by reference herein.

(7)

Filed on October 1, 2018 as an exhibit to Nuveen Dow 30^SM Dynamic Overwrite Fund’s Registration Statement on Form N-2 (File No. 333-226218) and incorporated by reference herein.

(8)

Filed on March 11, 2020 as an exhibit to Pre-Effective Amendment No. 1 to Nuveen California AMT-Free Quality Municipal Income Fund’s Registration Statement on Form N-2 (File No. 333-225399) and incorporated by reference herein.

(9)

Filed on August 24, 2020 as an exhibit to Nuveen California Municipal Value Fund’s Registration Statement on Form N-14 (File No. 333-248308) and incorporated by reference herein.

(10)

Filed on August 26, 2021 as an exhibit to Nuveen Dynamic Municipal Opportunities Fund’s Registration Statement on Form N-2 (File No. 333-259086) and incorporated by reference herein.

(11)

Filed on November 10, 2022 as an exhibit to Nuveen Municipal Credit Income Fund’s Registration Statement on Form N-14 (File No. 333-268294) and incorporated by reference herein.

(12)

Filed on September 7, 2023 as an exhibit to Nuveen AMT-Free Municipal Credit Income Fund’s Registration Statement on Form N-14 (File No. 333-274389) and incorporated by reference herein.

(13)

Filed on May 11, 2023 as an exhibit to the Registrant’s Registration Statement on Form N-14 (File No. 333-271820) and incorporated by reference herein.

(14)

Filed on March 19, 2021 as an exhibit to Post-Effective Amendment No. 1 to the Registrant’s Registration Statement on Form N-2 (File No. 333-254473) and incorporated by reference herein.

(15)

Filed on July 29, 2022 as an exhibit to Post-Effective Amendment No. 2 to Nuveen Enhanced High Yield Municipal Bond Fund’s Registration Statement on Form N-2 (File No. 333-231722) and incorporated by reference herein.

(16)

Filed on April 24, 2025 as an exhibit to the Registrant’s Registration Statement on Form N-14 (File No. 333-286736) and incorporated by reference herein.

(17)

Filed on June 11, 2025 as an exhibit to the Registrant’s Registration Statement on Form N-14 (File No. 333-286736) and incorporated by reference herein.

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Item 17. Undertakings

(1) The undersigned Registrant agrees that prior to any public reoffering of the securities registered through the use of a prospectus which is a part of this registration statement by any person or party who is deemed to be an underwriter within the meaning of Rule 145(c) of the Securities Act, the reoffering prospectus will contain the information called for by the applicable registration form for reofferings by persons who may be deemed underwriters, in addition to the information called for by the other items of the applicable form.

(2) The undersigned Registrant agrees that every prospectus that is filed under paragraph (1) above will be filed as a part of an amendment to the registration statement and will not be used until the amendment is effective, and that, in determining any liability under the Securities Act, each post-effective amendment shall be deemed to be a new registration statement for the securities offered therein, and the offering of the securities at that time shall be deemed to be the initial bona fide offering of them.

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SIGNATURES

As required by the Securities Act of 1933, the Registrant has duly caused this registration statement to be signed on its behalf by the undersigned, thereunto duly authorized in the City of Chicago and the State of Illinois, on the 21^st day of April, 2026.

	NUVEEN PREFERRED & INCOME OPPORTUNITIES FUND

	By:	/s/ Mark L. Winget
		Mark L. Winget
		Vice President and Secretary

As required by the Securities Act of 1933, this Registrant’s registration statement has been signed by the following persons in the capacities and on the dates indicated:

Signature	Capacity	Date

/s/ David J. Lamb	Chief Administrative Officer	April 21, 2026
David J. Lamb	(principal executive officer)

/s/ Mark Cardella	Vice President and Controller	April 21, 2026
Mark Cardella	(principal financial and accounting officer)
		By:	/s/ Mark L. Winget
	Chair of the Board and Trustee		Mark L. Winget
Robert L. Young*			Attorney-in-Fact
			April 21, 2026
	Trustee
Joseph A. Boateng*

	Trustee
Michael A. Forrester*

	Trustee
Thomas J. Kenny*

	Trustee
Amy B.R. Lancellotta*

	Trustee
Joanne T. Medero*

	Trustee
Albin F. Moschner*

	Trustee
John K. Nelson*

	Trustee
Loren M. Starr*

	Trustee
Matthew Thornton III*

	Trustee
Terence J. Toth*

	Trustee
Margaret L. Wolff*

An original power of attorney authorizing, among others, Mark L. Winget, Kevin J. McCarthy and Mark J. Czarniecki to execute this registration statement, and amendments thereto, for each of the trustees of the Registrant on whose behalf this registration statement is filed, has been executed and is Exhibit (16) which is incorporated by reference to the Registrant’s Registration Statement on Form N-14 (File No. 333-286736) filed on April 24, 2025.

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EXHIBIT INDEX

Exhibit No.	Name of Exhibit
(12)	Opinion and Consent of Vedder Price P.C. supporting the tax matters discussed in the Joint Proxy Statement/Prospectus.

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SEC Form POS EX filed by Nuveen Preferred & Income Opportunities Fund