SEC FORM 3

SEC FORM 3 SEC Form 3

FORM 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

INITIAL STATEMENT OF BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934
or Section 30(h) of the Investment Company Act of 1940

OMB APPROVAL

OMB Number:			3235-0104
Estimated average burden
hours per response:			0.5

1. Name and Address of Reporting Person^*

Maranian Jeffrey R

(Last)

(First)

(Middle)

C/O SUMMIT THERAPEUTICS INC.

ONE BROADWAY, 14TH FLOOR

(Street)

CAMBRIDGE

02142

(City)

(State)

(Zip)

2. Date of Event Requiring Statement (Month/Day/Year)
07/02/2021

3. Issuer Name and Ticker or Trading Symbol
Summit Therapeutics Inc. [ SMMT ]

4. Relationship of Reporting Person(s) to Issuer
(Check all applicable)

	Director	10% Owner
X	Officer (give title below)	Other (specify below)
VP, Corporate Controller

5. If Amendment, Date of Original Filed (Month/Day/Year)

6. Individual or Joint/Group Filing (Check Applicable Line)

X	Form filed by One Reporting Person
	Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Beneficially Owned
1. Title of Security (Instr. 4)	2. Amount of Securities Beneficially Owned (Instr. 4)	3. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	4. Nature of Indirect Beneficial Ownership (Instr. 5)

Table II - Derivative Securities Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 4)	2. Date Exercisable and Expiration Date (Month/Day/Year)		3. Title and Amount of Securities Underlying Derivative Security (Instr. 4)		4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
1. Title of Derivative Security (Instr. 4)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares	4. Conversion or Exercise Price of Derivative Security	5. Ownership Form: Direct (D) or Indirect (I) (Instr. 5)	6. Nature of Indirect Beneficial Ownership (Instr. 5)
Stock Option (right to buy)	11/22/2021	11/22/2030	Common Stock	112,500⁽¹⁾	4.4	D
Stock Option (right to buy)	11/22/2021	11/22/2030	Common Stock	112,500⁽²⁾	4.4	D
Stock Option (right to buy)	06/01/2022	06/16/2031	Common Stock	20,000⁽³⁾	6.61	D

Explanation of Responses:

1. The option was granted on November 22, 2020 pursuant to the Issuer's Stock Incentive Plan. The shares underlying the option are scheduled to vest in four equal annual installments, with the first such installment occuring on November 22, 2021.

2. The option was granted on November 22, 2020 pursuant to the Issuer's Stock Incentive Plan. The shares underlying the option are scheduled to vest in four equal annual installments, with the first such installment occuring on November 22, 2021, subject to the satisfaction of certain performance targets.

3. The option was granted on June 16, 2021 pursuant to the Issuer's Stock Incentive Plan. The shares underlying the option are scheduled to vest in two equal annual installments, with the first such installment occuring on June 1, 2022.

	/s/ Jeffrey R. Maranian	07/09/2021
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 5 (b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).
Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.
Persons who respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB Number.

SEC Form 3 filed by Maranian Jeffrey R