144: Filer Information

Filer CIK

0001114357

Filer CCC

XXXXXXXX

Is this a LIVE or TEST Filing?

LIVE

TEST

Submission Contact Information

Name

Phone

E-Mail Address

144: Issuer Information

Name of Issuer

Tempus AI, Inc.

SEC File Number

001-42130

Address of Issuer

600 West Chicago Avenue, Suite 510
Chicago
ILLINOIS
60654

Phone

800-976-5448

Name of Person for Whose Account the Securities are To Be Sold

Eric Lefkofsky

See the definition of "person" in paragraph (a) of Rule 144. Information is to be given not only as to the person for whose account the securities are to be sold but also as to all other persons included in that definition. In addition, information shall be given as to sales by all persons whose sales are required by paragraph (e) of Rule 144 to be aggregated with sales for the account of the person filing this notice.

Relationship to Issuer

Officer

Relationship to Issuer

Director

Relationship to Issuer

10% Stockholder

144: Securities Information

Title of the Class of Securities To Be Sold

Name and Address of the Broker

Number of Shares or Other Units To Be Sold

Aggregate Market Value

Number of Shares or Other Units Outstanding

Approximate Date of Sale

Name the Securities Exchange

Class A Common Stock

J.P. Morgan Securities LLC
270 Park Avenue, 10th Floor
New York � NY � 10017

250000

19507500

175390967

09/22/2026

NASDAQ

Furnish the following information with respect to the acquisition of the securities to be sold and with respect to the payment of all or any part of the purchase price or other consideration therefor:

144: Securities To Be Sold

Title of the Class

Date you Acquired

Nature of Acquisition Transaction

Name of Person from Whom Acquired

Is this a Gift?

Date Donor Acquired

Amount of Securities Acquired

Date of Payment

Nature of Payment *

Class A Common Stock

01/22/2025

Stock Compensation

Issuer

135000

01/22/2025

Compensation

Class A Common Stock

09/14/2017

Direct Investment

Issuer

57500

09/14/2017

Cash

Class A Common Stock

03/05/2020

Direct Investment

Issuer

7500

03/05/2020

Cash

Class A Common Stock

12/04/2025

Donation

Blue Media LLC who acquired the shares on 09/24/2015

50000

12/04/2025

Donation

* If the securities were purchased and full payment therefor was not made in cash at the time of purchase, explain in the table or in a note thereto the nature of the consideration given. If the consideration consisted of any note or other obligation, or if payment was made in installments describe the arrangement and state when the note or other obligation was discharged in full or the last installment paid.

Furnish the following information as to all securities of the issuer sold during the past 3 months by the person for whose account the securities are to be sold.

144: Securities Sold During The Past 3 Months

Name and Address of Seller

Title of Securities Sold

Date of Sale

Amount of Securities Sold

Gross Proceeds

Blue Media, LLC
C/o Tempus AI, Inc.
600 West Chicago Avenue, Suite 510
Chicago � IL � 60654

Class A Common Stock

06/29/2026

133000

7645208.81

Blue Media, LLC
C/o Tempus AI, Inc.
600 West Chicago Avenue, Suite 510
Chicago � IL � 60654

Class A Common Stock

07/28/2026

135000

5678417

Blue Media, LLC
C/o Tempus AI, Inc.
600 West Chicago Avenue, Suite 510
Chicago � IL � 60654

Class A Common Stock

08/25/2026

135000

9241867

Blue Media, LLC
C/o Tempus AI, Inc.
600 West Chicago Avenue, Suite 510
Chicago � IL � 60654

Class A Common Stock

09/17/2026

135000

10876976

Gray Media, LLC
C/o Tempus AI, Inc.
600 West Chicago Avenue, Suite 510
Chicago � IL � 60654

Class A Common Stock

06/29/2026

33250

1911302.2

Gray Media, LLC
C/o Tempus AI, Inc.
600 West Chicago Avenue, Suite 510
Chicago � IL � 60654

Class A Common Stock

07/28/2026

57500

2418585

Gray Media, LLC
C/o Tempus AI, Inc.
600 West Chicago Avenue, Suite 510
Chicago � IL � 60654

Class A Common Stock

08/25/2026

57500

3936351

Gray Media, LLC
C/o Tempus AI, Inc.
600 West Chicago Avenue, Suite 510
Chicago � IL � 60654

Class A Common Stock

09/17/2026

57500

4632786

Lefkofsky Family Foundation
C/o Tempus AI, Inc.
600 West Chicago Avenue, Suite 510
Chicago � IL � 60654

Class A Common Stock

07/28/2026

7500

315468

Lefkofsky Family Foundation
C/o Tempus AI, Inc.
600 West Chicago Avenue, Suite 510
Chicago � IL � 60654

Class A Common Stock

08/25/2026

7500

513437

Lefkofsky Family Foundation
C/o Tempus AI, Inc.
600 West Chicago Avenue, Suite 510
Chicago � IL � 60654

Class A Common Stock

09/17/2026

7500

604276

Vas.org Foundation
C/o Tempus AI, Inc.
600 West Chicago Avenue, Suite 510
Chicago � IL � 60654

Class A Common Stock

07/28/2026

50000

2103118

144: Remarks and Signature

Remarks

This form relates to sales by Blue Media, LLC (135,000 shares), Gray Media, LLC (57,500 shares), Lefkofsky Family Foundation (7,500 shares) and Vas.org Foundation (50,000 shares) of which Mr. Lefkofsky is the authorized signatory.

Date of Notice

09/22/2026

Date of Plan Adoption or Giving of Instruction, If Relying on Rule 10b5-1

03/08/2026

ATTENTION:

The person for whose account the securities to which this notice relates are to be sold hereby represents by signing this notice that he does not know any material adverse information in regard to the current and prospective operations of the Issuer of the securities to be sold which has not been publicly disclosed. If such person has adopted a written trading plan or given trading instructions to satisfy Rule 10b5-1 under the Exchange Act, by signing the form and indicating the date that the plan was adopted or the instruction given, that person makes such representation as of the plan adoption or instruction date.

Signature

/s/ J.P. Morgan Securities LLC as agent and attorney-in-fact for Eric Lefkofsky

144: Filer Information

Submission Contact Information

144: Issuer Information

144: Securities Information

144: Securities To Be Sold

144: Securities Sold During The Past 3 Months

144: Remarks and Signature

ATTENTION:

ATTENTION: Intentional misstatements or omission of facts constitute Federal Criminal Violations (See 18 U.S.C. 1001)