SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

SCHEDULE 13G

UNDER THE SECURITIES EXCHANGE ACT OF 1934

(Amendment No. 3)

Immunome, Inc.

(Name of Issuer)

Common Stock, $0.0001 par value per share

(Title of Class of Securities)

45257U108

(CUSIP Number)

12/31/2025

(Date of Event Which Requires Filing of this Statement)

Check the appropriate box to designate the rule pursuant to which this Schedule is filed:

Rule 13d-1(b)

Rule 13d-1(c)

Rule 13d-1(d)

SCHEDULE 13G

CUSIP No.

45257U108

Names of Reporting Persons

Redmile Group, LLC

Check the appropriate box if a member of a Group (see instructions)

(a)

(b)

Sec Use Only

Citizenship or Place of Organization

DELAWARE

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 5,718,385.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 5,718,385.00

Aggregate Amount Beneficially Owned by Each Reporting Person

5,718,385.00

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

Checkbox not checked

Percent of class represented by amount in row (9)

5.2 %

Type of Reporting Person (See Instructions)

IA, OO

Comment for Type of Reporting Person: Redmile Group, LLC's beneficial ownership of the Issuer's common stock ("Common Stock") is comprised of 5,718,385 shares of Common Stock owned by certain private investment vehicles managed by Redmile Group, LLC (the "Redmile Funds"). The reported securities may be deemed beneficially owned by Redmile Group, LLC as investment manager of the Redmile Funds. The reported securities may also be deemed beneficially owned by Jeremy C. Green as the principal of Redmile Group, LLC. Redmile Group, LLC and Mr. Green each disclaim beneficial ownership of these shares, except to the extent of its or his pecuniary interest in such shares, if any. Percentage based on the sum of (i) 91,710,277 shares of Common Stock outstanding as of November 3, 2025, as reported by the Issuer in its Form 10-Q for the quarterly period ended September 30, 2025 filed with the SEC on November 6, 2025 (the "Form 10-Q"), plus (ii) 18,625,000 shares of Common Stock issued and sold as of December 18, 2025, as reported by the Issuer in its Form 8-K filed with the SEC on December 17, 2025 (the "Form 8-K").

SCHEDULE 13G

CUSIP No.

45257U108

Names of Reporting Persons

Jeremy C. Green

Check the appropriate box if a member of a Group (see instructions)

(a)

(b)

Sec Use Only

Citizenship or Place of Organization

UNITED KINGDOM

Number of Shares Beneficially Owned by Each Reporting Person With:

5	Sole Voting Power 0.00
6	Shared Voting Power 5,718,385.00
7	Sole Dispositive Power 0.00
8	Shared Dispositive Power 5,718,385.00

Aggregate Amount Beneficially Owned by Each Reporting Person

5,718,385.00

Check box if the aggregate amount in row (9) excludes certain shares (See Instructions)

Checkbox not checked

Percent of class represented by amount in row (9)

5.2 %

Type of Reporting Person (See Instructions)

HC, IN

Comment for Type of Reporting Person: Jeremy C. Green's beneficial ownership of Common Stock is comprised of 5,718,385 shares of Common Stock owned by the Redmile Funds. The reported securities may be deemed beneficially owned by Redmile Group, LLC as investment manager of the Redmile Funds. The reported securities may also be deemed beneficially owned by Jeremy C. Green as the principal of Redmile Group, LLC. Redmile Group, LLC and Mr. Green each disclaim beneficial ownership of these shares, except to the extent of its or his pecuniary interest in such shares, if any. Percentage based on the sum of (i) 91,710,277 shares of Common Stock outstanding as of November 3, 2025, as reported in the Form 10-Q, plus (ii) 18,625,000 shares of Common Stock issued and sold as of December 18, 2025, as reported in the Form 8-K.

SCHEDULE 13G

Item 1.

(a)

Name of issuer:

Immunome, Inc.

(b)

Address of issuer's principal executive offices:

18702 N. Creek Parkway, Suite 100, Bothell, WA 98011

Item 2.

(a)

Name of person filing:

Redmile Group, LLC Jeremy C. Green

(b)

Address or principal business office or, if none, residence:

Redmile Group, LLC One Letterman Drive Building D, Suite D3-300 The Presidio of San Francisco San Francisco, California 94129 Jeremy C. Green c/o Redmile Group, LLC (NY Office) 45 W. 27th Street, Floor 11 New York, NY 10001

(c)

Citizenship:

Redmile Group, LLC: Delaware Jeremy C. Green: United Kingdom

(d)

Title of class of securities:

Common Stock, $0.0001 par value per share

(e)

CUSIP No.:

45257U108

Item 3.

If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a:

(a)

Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);

(b)

Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);

(c)

Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);

(d)

Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);

(e)

An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);

(f)

An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);

(g)

A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);

(h)

A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);

(i)

A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);

(j)

A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:

(k)

Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).

Item 4.

Ownership

(a)

Amount beneficially owned:

Redmile Group, LLC - 5,718,385 (1) Jeremy C. Green - 5,718,385 (1)

(b)

Percent of class:

Redmile Group, LLC - 5.2% (2) Jeremy C. Green - 5.2% (2)

(c)

Number of shares as to which the person has:

(i) Sole power to vote or to direct the vote:

Redmile Group, LLC - 0 Jeremy C. Green - 0

(ii) Shared power to vote or to direct the vote:

Redmile Group, LLC - 5,718,385 (1) Jeremy C. Green - 5,718,385 (1)

(iii) Sole power to dispose or to direct the disposition of:

Redmile Group, LLC - 0 Jeremy C. Green - 0

(iv) Shared power to dispose or to direct the disposition of:

Redmile Group, LLC - 5,718,385 (1) Jeremy C. Green - 5,718,385 (1) (1) Redmile Group, LLC's and Jeremy C. Green's beneficial ownership of the Issuer's Common Stock is comprised of 5,718,385 shares of Common Stock owned by the Redmile Funds. The reported securities may be deemed beneficially owned by Redmile Group, LLC as investment manager of the Redmile Funds. The reported securities may also be deemed beneficially owned by Jeremy C. Green as the principal of Redmile Group, LLC. Redmile Group, LLC and Mr. Green each disclaim beneficial ownership of these shares, except to the extent of its or his pecuniary interest in such shares, if any. (2) Percentage based on the sum of (i) 91,710,277 shares of Common Stock outstanding as of November 3, 2025, as reported in the Form 10-Q, plus (ii) 18,625,000 shares of Common Stock issued and sold as of December 18, 2025, as reported in the Form 8-K.

Item 5.

Ownership of 5 Percent or Less of a Class.

Not Applicable

Item 6.

Ownership of more than 5 Percent on Behalf of Another Person.

Not Applicable

Item 7.

Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person.

If a parent holding company has filed this schedule, pursuant to Rule 13d-1(b)(ii)(G), so indicate under Item 3(g) and attach an exhibit stating the identity and the Item 3 classification of the relevant subsidiary. If a parent holding company has filed this schedule pursuant to Rule 13d-1(c) or Rule 13d-1(d), attach an exhibit stating the identification of the relevant subsidiary.

See the response to Item 4.

Item 8.

Identification and Classification of Members of the Group.

Not Applicable

Item 9.

Notice of Dissolution of Group.

Not Applicable

Item 10.

Certifications:

By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11.

SIGNATURE

After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct.

Redmile Group, LLC

Signature:	/s/ Jeremy C. Green
Name/Title:	Managing Member
Date:	02/17/2026

Jeremy C. Green

Signature:	/s/ Jeremy C. Green
Name/Title:	Jeremy C. Green
Date:	02/17/2026

Amendment: SEC Form SCHEDULE 13G/A filed by Immunome Inc.