TSHA insider transactions

Director Stalfort John A Iii was granted 21,335 shares, increasing direct ownership by 2% to 1,176,559 units (SEC Form 4)

Director Sepp-Lorenzino Laura was granted 21,335 shares, increasing direct ownership by 20% to 127,178 units (SEC Form 4)

Director Long Alison S was granted 21,335 shares, increasing direct ownership by 20% to 127,178 units (SEC Form 4)

Director Donenberg Phillip B. was granted 21,335 shares, increasing direct ownership by 10% to 241,289 units (SEC Form 4)

SEC Form 4 filed by Nagendran Sukumar

CHIEF FINANCIAL OFFICER Alam Kamran sold $7,481 worth of shares (1,655 units at $4.52), decreasing direct ownership by 0.11% to 1,442,131 units (SEC Form 4)

President and Head of R&D Nagendran Sukumar sold $547,469 worth of shares (116,050 units at $4.72), decreasing direct ownership by 8% to 1,317,389 units (SEC Form 4)

Chief Executive Officer Nolan Sean P. sold $840,196 worth of shares (178,101 units at $4.72), decreasing direct ownership by 6% to 2,908,257 units (SEC Form 4)

CHIEF FINANCIAL OFFICER Alam Kamran sold $485,042 worth of shares (102,817 units at $4.72), decreasing direct ownership by 7% to 1,443,786 units (SEC Form 4)

CHIEF FINANCIAL OFFICER Alam Kamran was granted 359,000 shares, increasing direct ownership by 30% to 1,546,603 units (SEC Form 4)

President and Head of R&D Nagendran Sukumar sold $942,000 worth of shares (200,000 units at $4.71), was granted 427,000 shares and exercised 200,000 shares at a strike of $1.15, increasing direct ownership by 42% to 1,433,439 units (SEC Form 4)

Chief Executive Officer Nolan Sean P. was granted 1,008,000 shares, increasing direct ownership by 48% to 3,086,358 units (SEC Form 4)

President and Head of R&D Nagendran Sukumar exercised 370,172 shares at a strike of $1.52 and sold $1,695,906 worth of shares (370,172 units at $4.58) (SEC Form 4)

President and Head of R&D Nagendran Sukumar exercised 41,150 shares at a strike of $0.70 and sold $646,000 worth of shares (200,000 units at $3.23), decreasing direct ownership by 14% to 1,006,439 units (SEC Form 4)

President and Head of R&D Nagendran Sukumar sold $162,604 worth of shares (57,054 units at $2.85), decreasing direct ownership by 5% to 1,165,289 units (SEC Form 4)

CHIEF FINANCIAL OFFICER Alam Kamran sold $155,299 worth of shares (54,491 units at $2.85), decreasing direct ownership by 4% to 1,187,603 units (SEC Form 4)

Director Long Alison S was granted 56,623 shares, increasing direct ownership by 115% to 105,843 units (SEC Form 4)

Director Sepp-Lorenzino Laura was granted 56,623 shares, increasing direct ownership by 115% to 105,843 units (SEC Form 4)

Director Stalfort John A Iii was granted 56,623 shares, increasing direct ownership by 5% to 1,155,224 units (SEC Form 4)

Director Donenberg Phillip B. was granted 56,623 shares, increasing direct ownership by 35% to 219,954 units (SEC Form 4)

Large owner Manning Paul B bought $2,062,500 worth of shares (750,000 units at $2.75) (SEC Form 4)

Amendment: SEC Form 4 filed by CHIEF FINANCIAL OFFICER Alam Kamran

CHIEF FINANCIAL OFFICER Alam Kamran covered exercise/tax liability with 29,843 shares, decreasing direct ownership by 2% to 1,242,094 units (SEC Form 4)

Chief Executive Officer Nolan Sean P. was granted 892,500 shares, increasing direct ownership by 75% to 2,078,358 units (SEC Form 4)

President and Head of R&D Nagendran Sukumar was granted 324,500 shares, increasing direct ownership by 36% to 1,222,343 units (SEC Form 4)

CHIEF FINANCIAL OFFICER Alam Kamran was granted 431,000 shares, increasing direct ownership by 51% to 1,271,937 units (SEC Form 4)

Large owner Manning Paul B bought $2,999,999 worth of shares (1,333,333 units at $2.25) (SEC Form 4)

Long Alison S was granted 49,220 shares (SEC Form 4)

Stalfort John A Iii was granted 49,220 shares, increasing direct ownership by 5% to 1,098,601 units (SEC Form 4)

Donenberg Phillip B. was granted 49,220 shares, increasing direct ownership by 43% to 163,331 units (SEC Form 4)

Sepp-Lorenzino Laura was granted 49,220 shares (SEC Form 4)

Alam Kamran covered exercise/tax liability with 1,288 shares, decreasing direct ownership by 0.15% to 840,937 units (SEC Form 4)

Alam Kamran was granted 590,413 shares, increasing direct ownership by 234% to 842,225 units (SEC Form 4)

Nagendran Sukumar was granted 863,617 shares, increasing direct ownership by 2,523% to 897,843 units (SEC Form 4)

Nolan Sean P. was granted 1,184,688 shares, increasing direct ownership by 101,255% to 1,185,858 units (SEC Form 4)

SEC Form 4 filed by Alam Kamran

SEC Form 4 filed by Nagendran Sukumar

SEC Form 4 filed by Nolan Sean P.

Manning Paul B bought $163,000 worth of shares (100,000 units at $1.63) (SEC Form 4)

SEC Form 4 filed by Long Alison S

SEC Form 3 filed by new insider Long Alison S

SEC Form 4: Alam Kamran sold $76,890 worth of shares (33,000 units at $2.33), decreasing direct ownership by 11% to 258,042 units

SEC Form 4: Manning Paul B bought $14,820,000 worth of shares (16,466,667 units at $0.90)

SEC Form 4: Stalfort John A Iii bought $700,000 worth of shares (777,778 units at $0.90) and received a gift of 50,000 shares, increasing direct ownership by 72% to 1,049,381 units

SEC Form 4: Nolan Sean P. bought $400,000 worth of shares (444,444 units at $0.90)

SEC Form 4: Donenberg Phillip B. bought $100,000 worth of shares (111,111 units at $0.90), increasing direct ownership by 3,704% to 114,111 units

SEC Form 4 filed by Session R.A. Ii

SEC Form 4 filed by Sepp-Lorenzino Laura

SEC Form 4 filed by Reape Kathleen

SEC Form 4 filed by Donenberg Phillip B.

SEC Form 4 filed by Stalfort John A Iii

SEC Form 3: New insider Stalfort John A Iii claimed ownership of 1,105,893 shares

SEC Form 4 filed by Session R.A. Ii

SEC Form 4 filed by Session R.A. Ii

SEC Form 4 filed by Alam Kamran

SEC Form 4 filed by Nagendran Sukumar

SEC Form 4: Session R.A. Ii acquired 251,296 shares, increasing direct ownership by 3% to 9,420,842 units

SEC Form 4: Alam Kamran was granted 18,691 shares, increasing direct ownership by 7% to 284,812 units

SEC Form 4 filed by Nolan Sean P.

SEC Form 4 filed by Nagendran Sukumar