RPRX insider transactions

EVP & CFO Coyne Terrance P. sold $3,476,116 worth of Class A Ordinary Shares (64,399 units at $53.98) as part of a pre-agreed trading plan (SEC Form 4)

EVP, Research & Investments Urist Marshall sold $721,838 worth of Class A Ordinary Shares (13,684 units at $52.75) as part of a pre-agreed trading plan, decreasing direct ownership by 43% to 18,197 units (SEC Form 4)

Director Norden Gregory sold $161,385 worth of Class A Ordinary Shares (3,045 units at $53.00) as part of a pre-agreed trading plan, decreasing direct ownership by 2% to 191,803 units (SEC Form 4)

EVP, Research & Investments Urist Marshall sold $726,137 worth of Class A Ordinary Shares (13,684 units at $53.06) as part of a pre-agreed trading plan, decreasing direct ownership by 30% to 31,881 units (SEC Form 4)

CEO, Chairman of the Board Legorreta Pablo G. was granted 143,821 units of Class A Ordinary Shares, increasing direct ownership by 13% to 1,242,604 units (SEC Form 4)

EVP & CFO Coyne Terrance P. was granted 24,263 units of Class A Ordinary Shares (SEC Form 4)

EVP & Vice Chairman Hite Christopher was granted 24,263 units of Class A Ordinary Shares (SEC Form 4)

EVP, Research & Investments Urist Marshall was granted 18,197 units of Class A Ordinary Shares, increasing direct ownership by 66% to 45,565 units (SEC Form 4)

EVP & CFO Coyne Terrance P. sold $1,731,840 worth of Class A Ordinary Shares (34,791 units at $49.78) as part of a pre-agreed trading plan (SEC Form 4)

SEC Form 4 filed by Coyne Terrance P.

SEC Form 4 filed by Bassler Bonnie L

SEC Form 4 filed by Coyne Terrance P.

EVP & CFO Coyne Terrance P. sold $1,627,534 worth of Class A Ordinary Shares (34,791 units at $46.78) (SEC Form 4)

EVP & CFO Coyne Terrance P. sold $1,576,606 worth of Class A Ordinary Shares (34,791 units at $45.32) (SEC Form 4)

CEO, Chairman of the Board Legorreta Pablo G. was granted 157,828 units of Class A Ordinary Shares, increasing direct ownership by 17% to 1,098,783 units (SEC Form 4)

EVP & CFO Coyne Terrance P. was granted 26,626 units of Class A Ordinary Shares (SEC Form 4)

EVP & Vice Chairman Hite Christopher was granted 26,626 units of Class A Ordinary Shares (SEC Form 4)

EVP, Research & Investments Urist Marshall was granted 19,970 units of Class A Ordinary Shares, increasing direct ownership by 270% to 27,368 units (SEC Form 4)

EVP & CFO Coyne Terrance P. sold $10,360,814 worth of Class A Ordinary Shares (243,541 units at $42.54) (SEC Form 4)

EVP, Research & Investments Urist Marshall sold $821,810 worth of Class A Ordinary Shares (20,000 units at $41.09) (SEC Form 4)

EVP, Research & Investments Urist Marshall sold $805,110 worth of Class A Ordinary Shares (20,000 units at $40.26) (SEC Form 4)

EVP & CFO Coyne Terrance P. sold $2,737,940 worth of Class A Ordinary Shares (69,582 units at $39.35) (SEC Form 4)

EVP, Research & Investments Urist Marshall sold $790,346 worth of Class A Ordinary Shares (20,000 units at $39.52) (SEC Form 4)

EVP, Research & Investments Urist Marshall sold $815,634 worth of Class A Ordinary Shares (20,000 units at $40.78) (SEC Form 4)

SEC Form 3 filed by new insider Mcgivern Arthur Richard

EVP & CFO Coyne Terrance P. sold $2,673,041 worth of Class A Ordinary Shares (69,582 units at $38.42) (SEC Form 4)

EVP, Research & Investments Urist Marshall sold $769,650 worth of Class A Ordinary Shares (20,000 units at $38.48) (SEC Form 4)

Director Bassler Bonnie L was granted 967 units of Class A Ordinary Shares, increasing direct ownership by 1% to 73,132 units (SEC Form 4)

EVP, Research & Investments Urist Marshall sold $786,380 worth of Class A Ordinary Shares (20,000 units at $39.32) (SEC Form 4)

EVP, Research & Investments Urist Marshall sold $767,582 worth of Class A Ordinary Shares (20,000 units at $38.38) (SEC Form 4)

EVP, Investments & CLO Lloyd George W. sold $4,240,333 worth of Class A Ordinary Shares (110,000 units at $38.55) (SEC Form 4)

EVP, Research & Investments Urist Marshall sold $766,420 worth of Class A Ordinary Shares (20,000 units at $38.32) (SEC Form 4)

EVP & CFO Coyne Terrance P. sold $2,669,172 worth of Class A Ordinary Shares (69,582 units at $38.36) (SEC Form 4)

EVP, Research & Investments Urist Marshall sold $1,627,815 worth of Class A Ordinary Shares (41,576 units at $39.15), decreasing direct ownership by 71% to 7,398 units (SEC Form 4)

EVP, Investments & CLO Lloyd George W. sold $4,375,008 worth of Class A Ordinary Shares (110,000 units at $39.77) (SEC Form 4)

EVP & CFO Coyne Terrance P. sold $2,773,956 worth of Class A Ordinary Shares (69,582 units at $39.87) (SEC Form 4)

EVP, Research & Investments Urist Marshall sold $1,659,489 worth of Class A Ordinary Shares (41,575 units at $39.92), decreasing direct ownership by 42% to 25,640 units (SEC Form 4)

EVP & CFO Coyne Terrance P. sold $2,682,505 worth of Class A Ordinary Shares (69,582 units at $38.55) (SEC Form 4)

EVP, Investments & CLO Lloyd George W. sold $5,192,656 worth of Class A Ordinary Shares (135,426 units at $38.34), closing all direct ownership in the company (SEC Form 4)

EVP & CFO Coyne Terrance P. sold $2,735,329 worth of Class A Ordinary Shares (69,594 units at $39.30) (SEC Form 4)

CEO, Chairman of the Board Legorreta Pablo G. was granted 36,559 units of Class A Ordinary Shares, increasing direct ownership by 4% to 940,955 units (SEC Form 4)

EVP & CFO Coyne Terrance P. was granted 6,168 units of Class A Ordinary Shares (SEC Form 4)

EVP, Investments & CLO Lloyd George W. was granted 6,168 units of Class A Ordinary Shares (SEC Form 4)

EVP & Vice Chairman Hite Christopher was granted 6,168 units of Class A Ordinary Shares (SEC Form 4)

EVP, Research & Investments Urist Marshall was granted 4,626 units of Class A Ordinary Shares and converted options into 160,000 units of Class A Ordinary Shares, increasing direct ownership by 12% to 43,882 units (SEC Form 4)

Director Bassler Bonnie L was granted 1,047 units of Class A Ordinary Shares, increasing direct ownership by 1% to 72,165 units (SEC Form 4)

Director Norden Gregory sold $1,213,749 worth of Class A Ordinary Shares (33,500 units at $36.23) and converted options into 144,660 units of Class A Ordinary Shares, increasing direct ownership by 133% to 194,848 units (SEC Form 4)

CEO, Chairman of the Board Legorreta Pablo G. was granted 21,901 units of Class A Ordinary Shares, increasing direct ownership by 2% to 904,396 units (SEC Form 4)

EVP & CFO Coyne Terrance P. was granted 3,696 units of Class A Ordinary Shares (SEC Form 4)

EVP, Investments & CLO Lloyd George W. was granted 3,696 units of Class A Ordinary Shares (SEC Form 4)

EVP & Vice Chairman Hite Christopher was granted 3,696 units of Class A Ordinary Shares (SEC Form 4)

EVP, Research & Investments Urist Marshall was granted 2,772 units of Class A Ordinary Shares, increasing direct ownership by 8% to 39,256 units (SEC Form 4)

Director Weatherman Elizabeth H was granted 8,558 units of Class A Ordinary Shares (SEC Form 4)

Director Ho Carole was granted 8,558 units of Class A Ordinary Shares (SEC Form 4)

SEC Form 3 filed by new insider Weatherman Elizabeth H

SEC Form 3 filed by new insider Ho Carole

Director Fernandez Henry A was granted 1,064 units of Class A Ordinary Shares, increasing direct ownership by 2% to 65,324 units (SEC Form 4)

Director Bassler Bonnie L was granted 1,064 units of Class A Ordinary Shares, increasing direct ownership by 2% to 71,118 units (SEC Form 4)

SEC Form 4 filed by EVP & Vice Chairman Hite Christopher

SEC Form 4 filed by EVP, Research & Investments Urist Marshall