EWTX insider transactions

Amendment: SEC Form 4 filed by Chief Financial Officer Nofi Michael

Amendment: SEC Form 4 filed by CMO Donovan Joanne M.

Amendment: SEC Form 4 filed by Chief Scientific Officer Russell Alan J

Amendment: SEC Form 4 filed by General Counsel Moore John R

Amendment: SEC Form 4 filed by Chief Business Officer Derakhshan Behrad

SEC Form 4 filed by Chief Financial Officer Nofi Michael

General Counsel Moore John R converted options into 12,499 shares and sold $219,823 worth of shares (5,016 units at $43.82), increasing direct ownership by 73% to 17,697 units (SEC Form 4) (for tax liability)

CMO Donovan Joanne M. converted options into 12,812 shares and sold $412,703 worth of shares (9,441 units at $43.71) as part of a pre-agreed trading plan, increasing direct ownership by 64% to 8,625 units (SEC Form 4) (for tax liability)

Chief Scientific Officer Russell Alan J converted options into 12,812 shares and sold $258,042 worth of shares (5,901 units at $43.73), increasing direct ownership by 28% to 31,466 units (SEC Form 4) to satisfy withholding obligation

Chief Business Officer Derakhshan Behrad converted options into 13,281 shares and sold $223,424 worth of shares (5,100 units at $43.81), increasing direct ownership by 35% to 31,826 units (SEC Form 4) to cover taxes

President and CEO Koch Kevin converted options into 39,844 shares and sold $785,042 worth of shares (17,971 units at $43.68), increasing direct ownership by 71% to 52,488 units (SEC Form 4) (withholding obligation)

SEC Form 4 filed by Director Root Jonathan D

Chief Scientific Officer Russell Alan J exercised 200,000 shares at a strike of $0.36 and sold $7,881,402 worth of shares (200,000 units at $39.41) (SEC Form 4)

Director Fox Jonathan C was granted 319 shares, increasing direct ownership by 1% to 24,833 units (SEC Form 4)

SEC Form 4 filed by Director Brege Laura

SEC Form 4 filed by Director Thompson Peter A.

SEC Form 4 filed by Director Morris Arlene

SEC Form 4 filed by Director Edris Badreddin

SEC Form 4 filed by Director Martin Christopher Nathan

SEC Form 4 filed by Director Fox Jonathan C

CMO Donovan Joanne M. sold $2,092,063 worth of shares (55,230 units at $37.88) as part of a pre-agreed trading plan and exercised 50,000 shares at a strike of $7.08, decreasing direct ownership by 54% to 4,367 units (SEC Form 4)

SEC Form 4 filed by Fox Jonathan C

SEC Form 4 filed by Donovan Joanne M.

SEC Form 4 filed by Donovan Joanne M.

SEC Form 4 filed by Donovan Joanne M.

Director Edris Badreddin exercised 115,471 shares at a strike of $1.47 and sold $3,399,466 worth of shares (115,471 units at $29.44) (SEC Form 4)

Director Fox Jonathan C was granted 473 shares, increasing direct ownership by 2% to 24,175 units (SEC Form 4)

SEC Form 4 filed by Director Martin Christopher Nathan

SEC Form 3 filed by new insider Martin Christopher Nathan

Chief Scientific Officer Russell Alan J exercised 100,000 shares at a strike of $0.18 and sold $2,112,450 worth of shares (100,000 units at $21.12) (SEC Form 4)

Director Fox Jonathan C bought $199,403 worth of shares (10,700 units at $18.64), increasing direct ownership by 82% to 23,702 units (SEC Form 4)

SEC Form 4 filed by Chief Financial Officer Nofi Michael

SEC Form 3 filed by new insider Nofi Michael

Director Fox Jonathan C was granted 728 shares, increasing direct ownership by 6% to 13,002 units (SEC Form 4)

Chief Scientific Officer Russell Alan J exercised 100,000 shares at a strike of $0.18 and sold $1,459,760 worth of shares (100,000 units at $14.60) (SEC Form 4)

SEC Form 4 filed by Chief Development Officer Blaustein Robert

General Counsel Moore John R converted options into 5,781 shares and sold $28,097 worth of shares (2,098 units at $13.39), increasing direct ownership by 56% to 10,214 units (SEC Form 4)

Chief Business Officer Derakhshan Behrad converted options into 5,781 shares and sold $33,360 worth of shares (2,491 units at $13.39), increasing direct ownership by 16% to 23,645 units (SEC Form 4)

Chief Financial Officer Carruthers R Michael converted options into 5,781 shares and sold $19,124 worth of shares (1,428 units at $13.39), increasing direct ownership by 5% to 86,162 units (SEC Form 4)

Chief Scientific Officer Russell Alan J converted options into 5,781 shares and sold $25,539 worth of shares (1,907 units at $13.39), increasing direct ownership by 20% to 23,400 units (SEC Form 4)

President and CEO Koch Kevin converted options into 17,968 shares and sold $106,764 worth of shares (7,972 units at $13.39), increasing direct ownership by 48% to 30,615 units (SEC Form 4)

CMO Donovan Joanne M. converted options into 5,781 shares and sold $38,329 worth of shares (2,862 units at $13.39), increasing direct ownership by 13% to 25,361 units (SEC Form 4)

Director Fox Jonathan C was granted 858 shares, increasing direct ownership by 8% to 12,274 units (SEC Form 4)

SEC Form 4 filed by Director Brege Laura

SEC Form 4 filed by Director Edris Badreddin

SEC Form 4 filed by Director Morris Arlene

SEC Form 4 filed by Director Fox Jonathan C

SEC Form 4 filed by Director Root Jonathan D

SEC Form 4 filed by Director Thompson Peter A.

Chief Scientific Officer Russell Alan J converted options into 5,209 shares and sold $25,520 worth of shares (1,551 units at $16.45), increasing direct ownership by 25% to 18,521 units (SEC Form 4)

General Counsel Moore John R converted options into 5,209 shares and sold $31,757 worth of shares (1,930 units at $16.45), increasing direct ownership by 101% to 6,531 units (SEC Form 4)

President and CEO Koch Kevin converted options into 10,417 shares and sold $70,358 worth of shares (4,276 units at $16.45), increasing direct ownership by 42% to 20,619 units (SEC Form 4)

CMO Donovan Joanne M. converted options into 10,417 shares and sold $85,348 worth of shares (5,187 units at $16.45), increasing direct ownership by 32% to 21,588 units (SEC Form 4)

Chief Business Officer Derakhshan Behrad converted options into 5,209 shares and sold $27,824 worth of shares (1,691 units at $16.45), increasing direct ownership by 21% to 20,355 units (SEC Form 4)

Chief Financial Officer Carruthers R Michael converted options into 5,209 shares and sold $21,621 worth of shares (1,314 units at $16.45), increasing direct ownership by 5% to 81,014 units (SEC Form 4)

Director Thompson Peter A. bought $10,000,000 worth of shares (496,771 units at $20.13) (SEC Form 4)

Director Orbimed Advisors Llc bought $10,000,000 worth of shares (496,771 units at $20.13) (SEC Form 4)

Director Fox Jonathan C was granted 559 shares, increasing direct ownership by 5% to 11,416 units (SEC Form 4)

Chief Scientific Officer Russell Alan J exercised 200 shares at a strike of $0.18 and sold $6,004 worth of shares (200 units at $30.02) (SEC Form 4)

President and CEO Koch Kevin exercised 100 shares at a strike of $0.18 and sold $3,000 worth of shares (100 units at $30.00) (SEC Form 4)