ALKS insider transactions

EVP, CLO, Alkermes, Inc. Gaffin David Joseph sold $87,564 worth of Ordinary Shares (2,034 units at $43.05) as part of a pre-agreed trading plan, decreasing direct ownership by 0.88% to 229,524 units (SEC Form 4)

EVP R&D, Chief Medical Officer Hopkinson Craig C. sold $375,044 worth of Ordinary Shares (9,000 units at $41.67) as part of a pre-agreed trading plan and exercised 5,000 units of Ordinary Shares at a strike of $19.34, decreasing direct ownership by 5% to 77,389 units (SEC Form 4)

VP, Finance (Interim PAO) Parisi Samuel Joseph sold $687,007 worth of Ordinary Shares (16,217 units at $42.36) and exercised 16,217 units of Ordinary Shares at a strike of $19.48 (SEC Form 4)

Director Wright Christopher I converted options into 6,142 units of Ordinary Shares and covered exercise/tax liability with 1,475 units of Ordinary Shares, increasing direct ownership by 20% to 27,680 units (SEC Form 4)

Director Wilson Frank Anders covered exercise/tax liability with 1,475 units of Ordinary Shares and converted options into 6,142 units of Ordinary Shares, increasing direct ownership by 15% to 35,751 units (SEC Form 4)

Director Snyderman Nancy Lynn Md converted options into 6,142 units of Ordinary Shares and covered exercise/tax liability with 1,475 units of Ordinary Shares, increasing direct ownership by 44% to 15,395 units (SEC Form 4)

Director Mckeon Brian P converted options into 6,142 units of Ordinary Shares and covered exercise/tax liability with 1,475 units of Ordinary Shares, increasing direct ownership by 14% to 38,536 units (SEC Form 4)

Director Lurker Nancy converted options into 6,142 units of Ordinary Shares and covered exercise/tax liability with 1,475 units of Ordinary Shares, increasing direct ownership by 34% to 18,222 units (SEC Form 4)

Director Laurencin Cato T converted options into 6,142 units of Ordinary Shares and covered exercise/tax liability with 1,475 units of Ordinary Shares, increasing direct ownership by 16% to 33,769 units (SEC Form 4)

Amendment: SEC Form 4 filed by Director Gaynor Richard

Amendment: SEC Form 4 filed by Director Cooke Shane

Director Gaynor Richard converted options into 6,142 units of Ordinary Shares and covered exercise/tax liability with 1,475 units of Ordinary Shares, increasing direct ownership by 15% to 35,751 units (SEC Form 4)

Director Cooke Shane converted options into 6,142 units of Ordinary Shares and covered exercise/tax liability with 3,207 units of Ordinary Shares, increasing direct ownership by 3% to 106,679 units (SEC Form 4)

EVP, CLO, Alkermes, Inc. Gaffin David Joseph sold $67,529 worth of Ordinary Shares (2,034 units at $33.20) as part of a pre-agreed trading plan, decreasing direct ownership by 0.87% to 231,558 units (SEC Form 4)

EVP R&D, Chief Medical Officer Hopkinson Craig C. exercised 5,000 units of Ordinary Shares at a strike of $19.34 and sold $300,560 worth of Ordinary Shares (9,000 units at $33.40) as part of a pre-agreed trading plan, decreasing direct ownership by 5% to 81,389 units (SEC Form 4)

SEC Form 4 filed by Lurker Nancy

SEC Form 4 filed by Gaffin David Joseph

SEC Form 4 filed by Hopkinson Craig C.

SEC Form 4 filed by SVP, Chief Financial Officer Reed Joshua

SEC Form 4 filed by Director and CEO, Alkermes plc Pops Richard F

VP, Finance (Interim PAO) Parisi Samuel Joseph sold $201,808 worth of Ordinary Shares (6,890 units at $29.29), decreasing direct ownership by 47% to 7,717 units (SEC Form 4)

SVP, Chief Commercial Officer Nichols Christian Todd sold $180,000 worth of Ordinary Shares (6,000 units at $30.00), decreasing direct ownership by 5% to 109,769 units (SEC Form 4)

SEC Form 4 filed by EVP, Chief Operating Officer Jackson Blair Curtis

EVP R&D, Chief Medical Officer Hopkinson Craig C. exercised 5,000 units of Ordinary Shares at a strike of $19.34 and sold $267,485 worth of Ordinary Shares (9,000 units at $29.72), decreasing direct ownership by 4% to 89,389 units (SEC Form 4)

EVP, CLO, Alkermes, Inc. Gaffin David Joseph sold $120,108 worth of Ordinary Shares (4,068 units at $29.53), decreasing direct ownership by 2% to 235,626 units (SEC Form 4)

VP, Finance (Interim PAO) Parisi Samuel Joseph converted options into 2,747 units of Ordinary Shares and covered exercise/tax liability with 808 units of Ordinary Shares, increasing direct ownership by 15% to 14,607 units (SEC Form 4)

SVP, Chief Commercial Officer Nichols Christian Todd converted options into 5,410 units of Ordinary Shares and covered exercise/tax liability with 2,403 units of Ordinary Shares, increasing direct ownership by 3% to 115,769 units (SEC Form 4)

EVP, Chief Operating Officer Jackson Blair Curtis converted options into 8,322 units of Ordinary Shares and covered exercise/tax liability with 3,695 units of Ordinary Shares, increasing direct ownership by 2% to 241,308 units (SEC Form 4)

EVP R&D, Chief Medical Officer Hopkinson Craig C. converted options into 6,866 units of Ordinary Shares and covered exercise/tax liability with 3,049 units of Ordinary Shares, increasing direct ownership by 4% to 93,389 units (SEC Form 4)

EVP, CLO, Alkermes, Inc. Gaffin David Joseph converted options into 6,866 units of Ordinary Shares and covered exercise/tax liability with 3,049 units of Ordinary Shares, increasing direct ownership by 2% to 239,694 units (SEC Form 4)

VP, Finance (Interim PAO) Parisi Samuel Joseph converted options into 2,283 units of Ordinary Shares and covered exercise/tax liability with 672 units of Ordinary Shares, increasing direct ownership by 15% to 12,668 units (SEC Form 4)

SVP, Chief Commercial Officer Nichols Christian Todd converted options into 6,407 units of Ordinary Shares and covered exercise/tax liability with 2,845 units of Ordinary Shares, increasing direct ownership by 3% to 112,762 units (SEC Form 4)

EVP, Chief Operating Officer Jackson Blair Curtis converted options into 8,738 units of Ordinary Shares and covered exercise/tax liability with 3,880 units of Ordinary Shares, increasing direct ownership by 2% to 236,681 units (SEC Form 4)

EVP R&D, Chief Medical Officer Hopkinson Craig C. converted options into 7,689 units of Ordinary Shares and covered exercise/tax liability with 3,414 units of Ordinary Shares, increasing direct ownership by 5% to 89,572 units (SEC Form 4)

EVP, CLO, Alkermes, Inc. Gaffin David Joseph converted options into 7,689 units of Ordinary Shares and covered exercise/tax liability with 3,414 units of Ordinary Shares, increasing direct ownership by 2% to 235,877 units (SEC Form 4)

VP, Finance (Interim PAO) Parisi Samuel Joseph converted options into 5,025 units of Ordinary Shares and covered exercise/tax liability with 1,685 units of Ordinary Shares, increasing direct ownership by 43% to 11,057 units (SEC Form 4)

SVP, Chief Commercial Officer Nichols Christian Todd converted options into 12,400 units of Ordinary Shares and covered exercise/tax liability with 4,146 units of Ordinary Shares, increasing direct ownership by 8% to 109,200 units (SEC Form 4)

EVP, Chief Operating Officer Jackson Blair Curtis converted options into 18,197 units of Ordinary Shares and covered exercise/tax liability with 7,926 units of Ordinary Shares, increasing direct ownership by 5% to 231,823 units (SEC Form 4)

EVP R&D, Chief Medical Officer Hopkinson Craig C. converted options into 16,570 units of Ordinary Shares and covered exercise/tax liability with 6,911 units of Ordinary Shares, increasing direct ownership by 13% to 85,297 units (SEC Form 4)

EVP, CLO, Alkermes, Inc. Gaffin David Joseph converted options into 14,028 units of Ordinary Shares and covered exercise/tax liability with 5,533 units of Ordinary Shares, increasing direct ownership by 4% to 231,602 units (SEC Form 4)

Director and CEO, Alkermes plc Pops Richard F was granted 149,580 units of Ordinary Shares and covered exercise/tax liability with 62,230 units of Ordinary Shares, increasing direct ownership by 7% to 1,377,740 units (SEC Form 4)

SVP, Chief Commercial Officer Nichols Christian Todd was granted 21,127 units of Ordinary Shares and covered exercise/tax liability with 6,389 units of Ordinary Shares, increasing direct ownership by 17% to 100,946 units (SEC Form 4)

EVP, Chief Operating Officer Jackson Blair Curtis was granted 28,810 units of Ordinary Shares and covered exercise/tax liability with 8,626 units of Ordinary Shares, increasing direct ownership by 10% to 221,552 units (SEC Form 4)

EVP R&D, Chief Medical Officer Hopkinson Craig C. was granted 25,352 units of Ordinary Shares and covered exercise/tax liability with 7,454 units of Ordinary Shares, increasing direct ownership by 31% to 75,638 units (SEC Form 4)

EVP, CLO, Alkermes, Inc. Gaffin David Joseph was granted 25,352 units of Ordinary Shares and covered exercise/tax liability with 7,619 units of Ordinary Shares, increasing direct ownership by 9% to 223,107 units (SEC Form 4)

EVP R&D, Chief Medical Officer Hopkinson Craig C. exercised 5,000 units of Ordinary Shares at a strike of $19.34 and sold $305,384 worth of Ordinary Shares (9,000 units at $33.93), decreasing direct ownership by 6% to 57,740 units (SEC Form 4)

Director Cooke Shane sold $2,115,673 worth of Ordinary Shares (61,200 units at $34.57) and exercised 61,200 units of Ordinary Shares at a strike of $31.64 (SEC Form 4)

EVP R&D, Chief Medical Officer Hopkinson Craig C. exercised 5,000 units of Ordinary Shares at a strike of $19.34 and sold $150,005 worth of Ordinary Shares (5,000 units at $30.00) (SEC Form 4)

EVP R&D, Chief Medical Officer Hopkinson Craig C. sold $112,000 worth of Ordinary Shares (4,000 units at $28.00), decreasing direct ownership by 6% to 61,740 units (SEC Form 4)

EVP R&D, Chief Medical Officer Hopkinson Craig C. exercised 3,748 units of Ordinary Shares at a strike of $19.34 and sold $112,447 worth of Ordinary Shares (3,748 units at $30.00) (SEC Form 4)

SEC Form 4 filed by Alkermes plc

EVP R&D, Chief Medical Officer Hopkinson Craig C. exercised 5,000 units of Ordinary Shares at a strike of $19.34 and sold $273,442 worth of Ordinary Shares (9,000 units at $30.38), decreasing direct ownership by 5% to 69,740 units (SEC Form 4)

EVP R&D, Chief Medical Officer Hopkinson Craig C. exercised 5,000 units of Ordinary Shares at a strike of $19.34 and sold $283,776 worth of Ordinary Shares (9,000 units at $31.53), decreasing direct ownership by 5% to 73,740 units (SEC Form 4)

SEC Form 4 filed by SVP, Chief Financial Officer Reed Joshua

SEC Form 3 filed by new insider Reed Joshua

EVP, CLO, Alkermes, Inc. Gaffin David Joseph converted options into 2,014 units of Ordinary Shares and covered exercise/tax liability with 895 units of Ordinary Shares, increasing direct ownership by 0.55% to 205,374 units (SEC Form 4)

SVP, Chief Commercial Officer Nichols Christian Todd sold $210,143 worth of Ordinary Shares (6,667 units at $31.52), decreasing direct ownership by 7% to 86,208 units (SEC Form 4)

Director Wright Christopher I converted options into 3,301 units of Ordinary Shares and covered exercise/tax liability with 793 units of Ordinary Shares, increasing direct ownership by 12% to 23,013 units (SEC Form 4)

Director Wright Christopher I covered exercise/tax liability with 1,924 units of Ordinary Shares and converted options into 8,013 units of Ordinary Shares, increasing direct ownership by 42% to 20,505 units (SEC Form 4)

Director Wilson Frank Anders converted options into 8,013 units of Ordinary Shares and covered exercise/tax liability with 1,924 units of Ordinary Shares, increasing direct ownership by 24% to 31,084 units (SEC Form 4)