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Compare · MDGL vs NVS

MDGL vs NVS

Side-by-side comparison of Madrigal Pharmaceuticals Inc. (MDGL) and Novartis AG (NVS): market cap, price performance, sector, and recent activity on the wire.

Summary

  • Both MDGL and NVS operate in Biotechnology: Pharmaceutical Preparations (Health Care), so they compete in similar markets.
  • NVS is the larger of the two at $284.62B, about 25.3x MDGL ($11.23B).
  • Over the past year, MDGL is up 66.9% and NVS is up 24.1% - MDGL leads by 42.8 points.
  • MDGL has hit the wire 8 times in the past 4 weeks while NVS has been quiet.
  • NVS has more recent analyst coverage (25 ratings vs 22 for MDGL).
PerformanceMDGL+66.92%NVS+24.12%
2025-06-09+0.00%2026-06-08
MetricMDGLNVS
Company
Madrigal Pharmaceuticals Inc.
Novartis AG
Price
$467.16-4.07%
$146.50-1.72%
Market cap
$11.23B
$284.62B
1M return
-12.71%
+0.71%
1Y return
+66.92%
+24.12%
Industry
Biotechnology: Pharmaceutical Preparations
Biotechnology: Pharmaceutical Preparations
Exchange
NASDAQ
NYSE
IPO
2007
News (4w)
8
0
Recent ratings
22
25
MDGL

Madrigal Pharmaceuticals Inc.

Madrigal Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on the development and commercialization of therapeutic candidates for the treatment of cardiovascular, metabolic, and liver diseases. Its lead product candidate is MGL-3196, a liver-directed selective thyroid hormone receptor-ß agonist, which is in Phase III clinical trials for the treatment of non-alcoholic steatohepatitis. The company has research, development, and commercialization agreement with Hoffmann-La Roche. Madrigal Pharmaceuticals, Inc. is headquartered in West Conshohocken, Pennsylvania.

NVS

Novartis AG

Novartis AG researches, develops, manufactures, and markets healthcare products worldwide. The company operates through two segments, Innovative Medicines and Sandoz. The Innovative Medicines segment offers prescription medicines for patients and healthcare providers. It also provides ophthalmology, neuroscience, immunology, hepatology and dermatology, respiratory, established, and cardiovascular, renal and metabolism medicine products. The Sandoz segment provides active ingredients and finished dosage forms of small molecule pharmaceuticals to third parties across a range of therapeutic areas, as well as finished dosage form anti-infectives. It also provides active pharmaceutical ingredients and intermediates primarily antibiotics; protein- or other biotechnology-based products, including biosimilars; and biotechnology manufacturing services. Novartis AG has a license and collaboration agreement with Alnylam Pharmaceuticals to develop, manufacture, and commercialize inclisiran; an agreement with CureVac to manufacture COVID-19 vaccine candidate CVnCoV; a collaboration with Artios Pharma Limited to create next generation DDR cancer therapies; and a clinical collaboration with Kura Oncology, Inc. to evaluate the combination of Tipifarnib and Alpelisib in patients with head and neck squamous cell carcinoma. The company was incorporated in 1996 and is headquartered in Basel, Switzerland.

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