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Compare · CSTL vs HUM

CSTL vs HUM

Side-by-side comparison of Castle Biosciences Inc. (CSTL) and Humana Inc. (HUM): market cap, price performance, sector, and recent activity on the wire.

Summary

  • Both CSTL and HUM operate in Medical Specialities (Health Care), so they compete in similar markets.
  • HUM is the larger of the two at $45.53B, about 72.5x CSTL ($627.8M).
  • Over the past year, CSTL is up 7.3% and HUM is up 61.0% - HUM leads by 53.7 points.
  • CSTL has been more active in the news (18 items in the past 4 weeks vs 3 for HUM).
  • HUM has more recent analyst coverage (25 ratings vs 5 for CSTL).
PerformanceCSTL+7.32%HUM+60.97%
2025-06-16+0.00%2026-06-12
MetricCSTLHUM
Company
Castle Biosciences Inc.
Humana Inc.
Price
$20.68-1.43%
$379.28+2.84%
Market cap
$627.8M
$45.53B
1M return
+14.13%
+24.47%
1Y return
+7.32%
+60.97%
Industry
Medical Specialities
Medical Specialities
Exchange
NASDAQ
NYSE
IPO
2019
News (4w)
18
3
Recent ratings
5
25
CSTL

Castle Biosciences Inc.

Castle Biosciences, Inc., a commercial-stage dermatological cancer company, focuses to provide diagnostic and prognostic solutions for dermatological cancers. Its lead product is DecisionDx-Melanoma, a multi-gene expression profile (GEP) test to identify high-risk patients with stage I and II melanomas based on biological information from 31 genes within their tumor tissue. The company also offers DecisionDx-UM test, a proprietary GEP test that predicts the risk of metastasis for patients with uveal melanoma, a rare eye cancer; DecisionDx-SCC, a proprietary 40-gene expression profile test that uses an individual patient's tumor biology to predict individual risk of squamous cell carcinoma metastasis for patients with one or more risk factors; and DecisionDx DiffDx-Melanoma, a proprietary GEP test for suspicious pigmented lesions. It offers test services through physicians and their patients. The company was founded in 2007 and is headquartered in Friendswood, Texas.

HUM

Humana Inc.

Humana Inc., together with its subsidiaries, operates as a health and well-being company in the United States. It operates through Retail, Group and Specialty, and Healthcare Services segments. The company offers medical and supplemental benefit plans to individuals. It also has a contract with Centers for Medicare and Medicaid Services to administer the Limited Income Newly Eligible Transition prescription drug plan program; and contracts with various states to provide Medicaid, dual eligible, and long-term support services benefits. In addition, the company provides commercial fully-insured medical and specialty health insurance benefits comprising dental, vision, and other supplemental health benefits; and administrative services only products to individuals and employer groups, as well as military services, such as TRICARE T2017 East Region contract. Further, it offers pharmacy solutions, provider services, predictive modeling and informatics services, and clinical care services, such as home health and other services to its health plan members, as well as to third parties. As of December 31, 2020, the company had approximately 17 million members in medical benefit plans, as well as approximately 5 million members in specialty products. Humana Inc. was incorporated in 1964 and is headquartered in Louisville, Kentucky.

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