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Compare · CNC vs CSTL

CNC vs CSTL

Side-by-side comparison of Centene Corporation (CNC) and Castle Biosciences Inc. (CSTL): market cap, price performance, sector, and recent activity on the wire.

Summary

  • Both CNC and CSTL operate in Medical Specialities (Health Care), so they compete in similar markets.
  • CNC is the larger of the two at $32.19B, about 51.3x CSTL ($627.8M).
  • Over the past year, CNC is up 19.2% and CSTL is up 7.3% - CNC leads by 11.9 points.
  • CSTL has been more active in the news (18 items in the past 4 weeks vs 6 for CNC).
  • CNC has more recent analyst coverage (25 ratings vs 5 for CSTL).
PerformanceCNC+19.18%CSTL+7.32%
2025-06-16+0.00%2026-06-12
MetricCNCCSTL
Company
Centene Corporation
Castle Biosciences Inc.
Price
$65.17+2.54%
$20.68-1.43%
Market cap
$32.19B
$627.8M
1M return
+10.80%
+14.13%
1Y return
+19.18%
+7.32%
Industry
Medical Specialities
Medical Specialities
Exchange
NYSE
NASDAQ
IPO
2019
News (4w)
6
18
Recent ratings
25
5
CNC

Centene Corporation

Centene Corporation operates as a multi-national healthcare enterprise that provides programs and services to under-insured and uninsured individuals in the United States. Its Managed Care segment offers health plan coverage to individuals through government subsidized programs, including Medicaid, the State children's health insurance program, long-term services and support, foster care, and medicare-medicaid plans, which cover dually eligible individuals, as well as aged, blind, or disabled programs. Its health plans include primary and specialty physician care, inpatient and outpatient hospital care, emergency and urgent care, prenatal care, laboratory and X-ray, home-based primary care, transportation assistance, vision care, dental care, telehealth, immunization, specialty pharmacy, therapy, social work, nurse advisory, and care coordination services, as well as prescriptions and limited over-the-counter drugs, medical equipment, and behavioral health and abuse services. This segment also offers various individual, small group, and large group commercial healthcare products to employers and directly to members in the Managed Care segment. The company's Specialty Services segment provides pharmacy benefits management services; nurse advice line and after-hours support services; and vision and dental services, as well as staffing services to correctional systems and other government agencies; and services to Military Health System eligible beneficiaries. This segment offers its services and products to state programs, correctional facilities, healthcare organizations, employer groups, and other commercial organizations. The company provides its services through primary and specialty care physicians, hospitals, and ancillary providers. Centene Corporation was founded in 1984 and is headquartered in St. Louis, Missouri.

CSTL

Castle Biosciences Inc.

Castle Biosciences, Inc., a commercial-stage dermatological cancer company, focuses to provide diagnostic and prognostic solutions for dermatological cancers. Its lead product is DecisionDx-Melanoma, a multi-gene expression profile (GEP) test to identify high-risk patients with stage I and II melanomas based on biological information from 31 genes within their tumor tissue. The company also offers DecisionDx-UM test, a proprietary GEP test that predicts the risk of metastasis for patients with uveal melanoma, a rare eye cancer; DecisionDx-SCC, a proprietary 40-gene expression profile test that uses an individual patient's tumor biology to predict individual risk of squamous cell carcinoma metastasis for patients with one or more risk factors; and DecisionDx DiffDx-Melanoma, a proprietary GEP test for suspicious pigmented lesions. It offers test services through physicians and their patients. The company was founded in 2007 and is headquartered in Friendswood, Texas.

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