PRVL

SEC Form SC 13G/A filed

SEC Form SC 13G/A filed

SEC Form SC 13G/A filed

SEC Form SC 13G/A filed

SEC Form 15-12B filed

SEC Form SC 13G filed

SEC Form EFFECT filed

SEC Form 4 filed by Llc Advisors Orbimed

SEC Form 4: Asa Abeliovich decreased ownership by 100% to 0 units

SEC Form 4 filed by M Timothy Adams

SEC Form 4 filed by H. William Carson

SEC Form 4 filed by Yong Dai

SEC Form 4 filed by Franz Hefti

SEC Form 4 filed by Brett Kaplan

SEC Form 4: Emily Minkow decreased ownership by 100% to 0 units

SEC Form 4 filed by Francois Nader

SEC Form 4 filed by M. Kira Schwartz

SEC Form 4 filed by Jeffrey Sevigny

SEC Form 4 filed by Morgan Sheng

SEC Form 4 filed by Ran Nussbaum

SEC Form 4 filed by L Carl Gordon

SEC Form 4 filed by A. Peter Thompson

SEC Form S-8 POS filed

SEC Form S-8 POS filed

SEC Form POS AM filed