KRYS - SEC Form 4 insider transactions

President, R&D Krishnan Suma sold $7,702,825 worth of shares (25,000 units at $308.11) as part of a pre-agreed trading plan, decreasing direct ownership by 2% to 1,378,155 units (SEC Form 4)

President and CEO Krishnan Krish S sold $7,702,984 worth of shares (25,000 units at $308.12) as part of a pre-agreed trading plan, decreasing direct ownership by 2% to 1,450,253 units (SEC Form 4)

EVP, General Counsel Thomas John Charles sold $193,903 worth of shares (642 units at $302.03) as part of a pre-agreed trading plan, closing all direct ownership in the company (SEC Form 4)

President, R&D Krishnan Suma sold $6,580,270 worth of shares (25,000 units at $263.21), decreasing direct ownership by 2% to 1,403,155 units (SEC Form 4)

President and CEO Krishnan Krish S sold $6,579,164 worth of shares (25,000 units at $263.17), decreasing direct ownership by 2% to 1,475,253 units (SEC Form 4)

Chief Accounting Officer Romano Kathryn converted options into 8,050 shares, covered exercise/tax liability with 3,502 shares and sold $200,700 worth of shares (750 units at $267.60), increasing direct ownership by 20% to 22,366 units (SEC Form 4)

President, R&D Krishnan Suma converted options into 67,225 shares and covered exercise/tax liability with 30,584 shares, increasing direct ownership by 1% to 1,428,155 units (SEC Form 4)

President and CEO Krishnan Krish S covered exercise/tax liability with 30,584 shares and converted options into 67,225 shares, increasing direct ownership by 2% to 1,500,253 units (SEC Form 4)

Director Janney Daniel sold $3,252,824 worth of shares (11,803 units at $275.59) (SEC Form 4)

Director Janney Daniel exercised 37,895 shares at a strike of $2.46 and sold $16,149,383 worth of shares (60,161 units at $268.44) (SEC Form 4)

Director Rossi Dino A sold $4,953,694 worth of shares (18,950 units at $261.41) and exercised 18,950 shares at a strike of $8.79 (SEC Form 4)

Chief Accounting Officer Romano Kathryn exercised 12,500 shares at a strike of $63.55, sold $3,401,705 worth of shares (12,500 units at $272.14) and gifted 750 shares, decreasing direct ownership by 4% to 18,568 units (SEC Form 4)

President, R&D Krishnan Suma sold $11,007,333 worth of shares (50,000 units at $220.15) and gifted 5,000 shares, decreasing direct ownership by 2% to 1,413,711 units (SEC Form 4)

President and CEO Krishnan Krish S sold $11,007,447 worth of shares (50,000 units at $220.15) and gifted 5,000 shares, decreasing direct ownership by 2% to 1,478,056 units (SEC Form 4)

President, R&D Krishnan Suma sold $5,395,001 worth of shares (35,873 units at $150.39), decreasing direct ownership by 1% to 1,438,711 units (SEC Form 4)

President and CEO Krishnan Krish S sold $5,395,001 worth of shares (35,873 units at $150.39), decreasing direct ownership by 1% to 1,508,056 units (SEC Form 4)

President, R&D Krishnan Suma sold $2,122,835 worth of shares (14,127 units at $150.27), decreasing direct ownership by 0.48% to 1,456,711 units (SEC Form 4)

President and CEO Krishnan Krish S sold $2,122,835 worth of shares (14,127 units at $150.27), decreasing direct ownership by 0.46% to 1,525,929 units (SEC Form 4)

SEC Form 4 filed by Director Gangolli Julian S

SEC Form 4 filed by Director Sutherland Everett Rand

SEC Form 4 filed by Director Janney Daniel

SEC Form 4 filed by Director Mason Christopher

SEC Form 4 filed by Director Rossi Dino A

SEC Form 4 filed by Director Mazzacco Catherine

President, R&D Krishnan Suma sold $8,889,525 worth of shares (50,000 units at $177.79), decreasing direct ownership by 2% to 1,463,711 units (SEC Form 4)

President and CEO Krishnan Krish S sold $8,889,525 worth of shares (50,000 units at $177.79), decreasing direct ownership by 2% to 1,533,056 units (SEC Form 4)

Chief Accounting Officer Romano Kathryn covered exercise/tax liability with 8,054 shares, sold $131,415 worth of shares (750 units at $175.22) and converted options into 12,500 shares, increasing direct ownership by 24% to 19,318 units (SEC Form 4)

President, R&D Krishnan Suma covered exercise/tax liability with 43,877 shares and converted options into 77,500 shares, increasing direct ownership by 0.87% to 1,488,711 units (SEC Form 4)

President and CEO Krishnan Krish S covered exercise/tax liability with 43,877 shares and converted options into 77,500 shares, increasing direct ownership by 1% to 1,558,056 units (SEC Form 4)

President, R&D Krishnan Suma sold $8,240,023 worth of shares (50,000 units at $164.80), decreasing direct ownership by 2% to 1,475,882 units (SEC Form 4)

President and CEO Krishnan Krish S sold $8,240,023 worth of shares (50,000 units at $164.80), decreasing direct ownership by 2% to 1,537,262 units (SEC Form 4)

President, R&D Krishnan Suma sold $9,888,276 worth of shares (50,000 units at $197.77), decreasing direct ownership by 2% to 1,500,882 units (SEC Form 4)

President and CEO Krishnan Krish S sold $9,888,276 worth of shares (50,000 units at $197.77), decreasing direct ownership by 2% to 1,562,262 units (SEC Form 4)

Director Rossi Dino A gifted 5,000 shares, decreasing direct ownership by 6% to 78,691 units (SEC Form 4)

SEC Form 4 filed by Director Gangolli Julian S

SEC Form 4 filed by Director Janney Daniel

SEC Form 4 filed by Director Mason Christopher

SEC Form 4 filed by Director Mazzacco Catherine

SEC Form 4 filed by Director Sutherland Everett Rand

SEC Form 4 filed by Director Rossi Dino A

President, R&D Krishnan Suma sold $8,788,062 worth of shares (50,000 units at $175.76), decreasing direct ownership by 2% to 1,525,882 units (SEC Form 4)

President and CEO Krishnan Krish S sold $8,788,062 worth of shares (50,000 units at $175.76), decreasing direct ownership by 2% to 1,587,262 units (SEC Form 4)

Gangolli Julian S sold $3,282,690 worth of shares (20,000 units at $164.13) and exercised 20,000 shares at a strike of $22.75 (SEC Form 4)

Krishnan Suma sold $8,547,719 worth of shares (50,000 units at $170.95), decreasing direct ownership by 2% to 1,550,882 units (SEC Form 4)

Krishnan Krish S sold $8,547,719 worth of shares (50,000 units at $170.95), decreasing direct ownership by 2% to 1,612,262 units (SEC Form 4)

Romano Kathryn exercised 10,000 shares at a strike of $31.77, sold $829,417 worth of shares (5,000 units at $165.88) and covered exercise/tax liability with 2,314 shares, increasing direct ownership by 21% to 15,622 units (SEC Form 4)

Romano Kathryn exercised 7,500 shares at a strike of $63.55 and sold $1,245,381 worth of shares (7,500 units at $166.05) (SEC Form 4)

Krishnan Suma converted options into 20,000 shares and covered exercise/tax liability with 9,256 shares, increasing direct ownership by 0.26% to 1,575,882 units (SEC Form 4)

Krishnan Krish S converted options into 20,000 shares and covered exercise/tax liability with 9,256 shares, increasing direct ownership by 0.41% to 1,637,262 units (SEC Form 4)

Krishnan Suma covered exercise/tax liability with 2,353 shares, decreasing direct ownership by 0.15% to 1,571,853 units (SEC Form 4)

Krishnan Krish S covered exercise/tax liability with 3,791 shares, decreasing direct ownership by 0.23% to 1,630,547 units (SEC Form 4)

Romano Kathryn exercised 10,000 shares at a strike of $52.26, sold $1,107,180 worth of shares (8,087 units at $136.91) and covered exercise/tax liability with 1,533 shares, increasing direct ownership by 3% to 12,936 units (SEC Form 4)

Romano Kathryn sold $325,000 worth of shares (2,500 units at $130.00) and exercised 2,500 shares at a strike of $52.26 (SEC Form 4)

Krishnan Suma sold $5,283,291 worth of shares (50,000 units at $105.67), decreasing direct ownership by 2% to 1,574,206 units (SEC Form 4)

Krishnan Krish S sold $5,283,291 worth of shares (50,000 units at $105.67), decreasing direct ownership by 2% to 1,634,338 units (SEC Form 4)

SEC Form 4: Krishnan Suma sold $6,361,680 worth of shares (50,000 units at $127.23), decreasing direct ownership by 2% to 1,599,206 units

SEC Form 4: Krishnan Krish S sold $6,361,680 worth of shares (50,000 units at $127.23), decreasing direct ownership by 1% to 1,659,338 units

SEC Form 4 filed by Mazzacco Catherine

SEC Form 4 filed by Sutherland Everett Rand

SEC Form 4 filed by Rossi Dino A