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KPTI

NASDAQ

Karyopharm Therapeutics Inc.

SectorHealth CareIndustryBiotechnology: Pharmaceutical PreparationsIPO2013
$8.51-0.56 (-6.17%)
News25/Ratings12

Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company pioneering novel cancer therapies, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases. Its Selective Inhibitor of Nuclear Export (SINE) compounds function by binding with and inhibiting the nuclear export protein XPO1. The company's lead compound, XPOVIO (selinexor), is approved in the U.S. in various hematologic malignancy indications, including in combination with Velcade (bortezomib) and dexamethasone for the treatment of adult patients with multiple myeloma after at least one prior therapy, in combination with dexamethasone for the treatment of adult patients with heavily pretreated multiple myeloma and as a monotherapy for the treatment of adult patients with relapsed or refractory diffuse large B-cell lymphoma. Its NEXPOVIO (selinexor) has also been granted conditional marketing authorization in combination with dexamethasone for adult patients with heavily pretreated multiple myeloma by the European Commission. In addition, the company's SINE compounds also show biological activity in models of neurodegeneration, inflammation, autoimmune disease, certain viruses, and wound-healing. Further, it also has various investigational programs in clinical or preclinical development. Karyopharm Therapeutics Inc. was incorporated in 2008 and is headquartered in Newton, Massachusetts.

Price$8.51-0.76 (-8.20%)
01:30 PM07:45 PM
News · 26 weeks72-17%
2025-12-14: 02025-12-21: 02025-12-28: 22026-01-04: 12026-01-11: 22026-01-18: 12026-01-25: 12026-02-01: 92026-02-08: 52026-02-15: 32026-02-22: 02026-03-01: 62026-03-08: 12026-03-15: 02026-03-22: 42026-03-29: 22026-04-05: 02026-04-12: 22026-04-19: 22026-04-26: 02026-05-03: 32026-05-10: 132026-05-17: 02026-05-24: 102026-05-31: 52026-06-07: 0
2025-12-142026-06-07
Mix4190d
  • Insider13(32%)
  • Other12(29%)
  • SEC Filings12(29%)
  • Earnings4(10%)

Latest news

25 items

KPTI FAQ

7 questions
  • What does Karyopharm Therapeutics Inc. do?
    Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company pioneering novel cancer therapies, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases. Its Selective Inhibitor of Nuclear Export (SINE) compounds function by binding with and inhibiting the nuclear export protein XPO1. The company's lead compound, XPOVIO (selinexor), is approved in the U.S. in various hematologic malignancy indications, including in combination with Velcade (bortezomib) and dexamethasone for the treatment of adult patients with...
  • Where does KPTI stock trade?
    Karyopharm Therapeutics Inc. (KPTI) is listed on NASDAQ.
  • What sector and industry is KPTI in?
    Karyopharm Therapeutics Inc. operates in the Health Care sector, Biotechnology: Pharmaceutical Preparations industry.
  • When did Karyopharm Therapeutics Inc. go public?
    Karyopharm Therapeutics Inc. (KPTI) completed its IPO in 2013.
  • What are analysts saying about KPTI?
    Karyopharm Therapeutics Inc. has had 8 recent analyst actions on file. The most recent action was from Rodman & Renshaw: Buy with a $2800.00 price target on 2026-03-10. Recent price targets range from $800.00 to $2800.00.
  • What companies are similar to KPTI?
    Notable peers in the same industry include LLY (Eli Lilly and Company), AZN (AstraZeneca PLC), JNJ (Johnson & Johnson), ABBV (AbbVie Inc.), MRK (Merck & Company Inc.). Compare KPTI side-by-side with any of them on Quantisnow.
  • How can I track KPTI on Quantisnow?
    Quantisnow aggregates Karyopharm Therapeutics Inc.'s SEC filings, analyst ratings, insider transactions, FDA approvals, and press releases the moment they hit the wire (Wall Street's wire, on your screen.). Follow KPTI to receive live email and push alerts on every new disclosure.